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Nadal-Nicolás Francisco Manuel

2 articles in GJC

2 articles in GJC

1.

Inherited Photoreceptor Degeneration Causes the Death of Melanopsin-Positive Retinal Ganglion Cells and Increases Their Coexpression of Brn3a.

García-Ayuso Diego, Di Pierdomenico Johnny, Esquiva Gema, Nadal-Nicolás Francisco Manuel, Pinilla Isabel, Cuenca Nicolás et al.

Invest Ophthalmol Vis SciJul 201538 citationsBasic Science

Inherited photoreceptor degeneration causes secondary loss of melanopsin-positive RGCs. Surviving cells show reduced dendrites but increased Brn3a coexpression, suggesting a survival mechanism relevant for vision preservation in retinal diseases.

2.

Sectorial loss of retinal ganglion cells in inherited photoreceptor degeneration is due to RGC death.

García-Ayuso Diego, Salinas-Navarro Manuel, Nadal-Nicolás Francisco Manuel, Ortín-Martínez Arturo, Agudo-Barriuso Marta, Vidal-Sanz Manuel et al.

Br J OphthalmolMar 201431 citationsBasic Science

In aged rats with inherited photoreceptor degeneration, sectorial retinal ganglion cell loss is primarily caused by RGC death, though retrograde transport issues also contribute at later stages.

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