Ooto Sotaro

Muraoka Yuki, Uji Akihito, Ishikura Masaharu, Iida Yuto, Ooto Sotaro, Tsujikawa Akitaka

HR-OCTA differentiated four macular retinal vessel layers, revealing distinct microcirculation units like central radial peripapillary capillaries. This enhances understanding of retinal blood supply in health and disease.

Hata Masayuki, Yamashiro Kenji, Ooto Sotaro, Oishi Akio, Tamura Hiroshi, Miyata Manabu et al.

This study found pachychoroid neovasculopathy has lower intraocular VEGF than nAMD, suggesting different angiogenesis mechanisms. Lower VEGF predicted better anti-VEGF response in PNV, guiding treatment expectations.

Hasegawa Tomoko, Ooto Sotaro, Takayama Kohei, Makiyama Yukiko, Akagi Tadamichi, Ikeda Hanako O et al.

This study found cone photoreceptor integrity (density, organization) was preserved in glaucoma patients, even with visual field loss, suggesting cones are resilient. This challenges assumptions about early cone damage.

Muraoka Yuki, Tsujikawa Akitaka, Hata Masayuki, Yamashiro Kenji, Ellabban Abdallah A, Takahashi Ayako et al.

This study found paravascular inner retinal defects (PIRDs) are common in high myopia or with epiretinal membranes, often causing corresponding visual field loss. This highlights the functional impact of these retinal changes.

Ooto Sotaro, Ellabban Abdallah A, Ueda-Arakawa Naoko, Oishi Akio, Tamura Hiroshi, Yamashiro Kenji et al.

This study found reticular pseudodrusen (RPD) are associated with reduced retinal sensitivity, best detected by infrared imaging. This suggests RPD, a common AMD precursor, functionally impairs the retina.

Takayama Kohei, Ooto Sotaro, Hangai Masanori, Ueda-Arakawa Naoko, Yoshida Sachiko, Akagi Tadamichi et al.

Adaptive optics imaging revealed narrower retinal nerve fiber bundles in glaucoma, even in early stages, correlating with visual field loss. This suggests AO SLO could detect early glaucoma damage.

Nukada Kazuyuki, Hangai Masanori, Ooto Sotaro, Yoshikawa Munemitsu, Yoshimura Nagahisa

Macular hole surgery with ILM peeling causes deep inner retinal damage, often beyond the DONFL appearance, which may impact retinal sensitivity, highlighting potential functional consequences.

Akagi Tadamichi, Hangai Masanori, Takayama Kohei, Nonaka Atsushi, Ooto Sotaro, Yoshimura Nagahisa

AOSLO better visualizes lamina cribrosa pores; glaucomatous eyes show larger pore areas, correlating with axial length and IOP, suggesting its utility for glaucoma assessment.

Kusuhara Sentaro, Ooto Sotaro, Kimura Daisaku, Itoi Kyoko, Mukuno Hirokazu, Miyamoto Noriko et al.

This study found 23-gauge vitrectomy with SF6 gas leads to faster gas dissipation than 20-gauge, potentially requiring sutures for comparable tamponade duration, impacting surgical planning.

Murakami Tomoaki, Akimoto Masayuki, Ooto Sotaro, Suzuki Takuya, Ikeda Hanako, Kawagoe Naoaki et al.

This RP study found abnormal autofluorescence patterns correlate with photoreceptor loss on OCT, suggesting different disease progression mechanisms.