Tsujikawa Akitaka

Akada Masahiro, Hata Masayuki, Muraoka Yuki, Ishihara Kenji, Kadomoto Shin, Ueshima Hiroaki et al.

This study found ARN incidence in Japan matched UK data, with early, intensive surgical management and frequent reoperations, highlighting the need for prompt clinical triage and resource planning.

Sun Chunxiao, Ikeda Hanako O, Miyake Masahiro, Suda Kenji, Kameda Takanori, Akagi Tadamichi et al.

This study found three ab interno trabeculotomy techniques offer similar IOP reduction and complication rates. Clinically, device choice doesn't significantly impact outcomes, but wider incisions increase hyphema risk.

Hara Tomoyo, Ikeda Hanako O, Numa Shogo, Miyake Masahiro, Suda Kenji, Kameda Takanori et al.

This study compared Ahmed and Baerveldt glaucoma implants in Japanese patients, finding similar IOP outcomes but more complications, especially hypotony, with Baerveldt, influencing device choice based on glaucoma type.

Murata Mariko, Miyake Masahiro, Suda Kenji, Mori Yuki, Morino Kazuya, Okayama Wakako et al.

Highly myopic eyes continue axial elongation (0.031 mm/year), but this slows with age and baseline axial length interaction. Cataract surgery also slows elongation. Genetic scores had limited adult predictive value.

Suda Kenji, Miyake Masahiro, Akagi Tadamichi, Ikeda Hanako Ohashi, Kameda Takanori, Hasegawa Tomoko et al.

This study found longer axial length (≥27.7mm) correlates with advanced visual field loss in young POAG patients, highlighting its clinical significance for assessing severe glaucoma risk.

Xiang Ran, Muraoka Yuki, Kogo Takahiro, Mori Yuki, Miyake Masahiro, Hidaka Yu et al.

OCT revealed retinal vessel structural changes with age, sex, and BMI, showing age-related arterial diameter U-shapes and venous narrowing. This highlights OCT's potential for assessing retinal vascular health linked to systemic factors.

Kishi Yuka, Ikeda Hanako O, Miyata Manabu, Numa Shogo, Kamei Takuro, Tsujikawa Akitaka

This study found outer retinal tubulations in Bietti crystalline dystrophy correlate with visual field loss severity, but not progression or retinal volume, suggesting their role in advanced disease.

Ikeda Hanako O, Hasegawa Tomoko, Abe Hiroyasu, Amino Yoko, Nakagawa Takayuki, Tada Harue et al.

Oral BCAAs for retinitis pigmentosa showed no significant visual field benefit, but a trend toward slower retinal degeneration was observed. BCAAs were safe, warranting further larger studies.

Takahashi Ayako, Muraoka Yuki, Koyasu Sho, Arakawa Yoshiki, Nakamura Eijiro, Tsujikawa Akitaka

OCTA revealed a novel, flat retinal hemangioblastoma type in VHL disease, distinct from classic nodular forms. This improves early detection of these often subtle lesions, aiding management.

Iwai Sachiko, Hasegawa Tomoko, Ikeda Hanako Ohashi, Tsujikawa Akitaka

BCAAs were studied for their ATP-boosting mechanism. They promote glucose transporter translocation to the cell surface, increasing glucose uptake and ATP production, which is relevant for treating glaucoma and retinal degeneration.

Kido Ai, Miyake Masahiro, Akagi Tadamichi, Ikeda Hanako Ohashi, Kameda Takanori, Suda Kenji et al.

This study found topical beta-blockers for glaucoma did not significantly increase asthma attacks in patients with asthma, suggesting they might be an option when other treatments fail.

Suda Kenji, Akagi Tadamichi, Ikeda Hanako Ohashi, Kameda Takanori, Hasegawa Tomoko, Miyake Masahiro et al.

Atopic dermatitis linked to severe visual field loss in younger glaucoma patients on steroids. This highlights the need for earlier, reinforced eye screening in atopic dermatitis patients.

Morino Kazuya, Murakami Tomoaki, Dodo Yoko, Yasukura Shota, Yoshitake Tatsuya, Fujimoto Masahiro et al.

This study found extramacular white spots in diabetic retinopathy represent deeper, more extensive nonperfusion than macular spots, aiding in differentiating and understanding diabetic capillary nonperfusion patterns.

Muraoka Yuki, Uji Akihito, Ishikura Masaharu, Iida Yuto, Ooto Sotaro, Tsujikawa Akitaka

HR-OCTA differentiated four macular retinal vessel layers, revealing distinct microcirculation units like central radial peripapillary capillaries. This enhances understanding of retinal blood supply in health and disease.

Numa Shogo, Akagi Tadamichi, Uji Akihito, Suda Kenji, Nakanishi Hideo, Kameda Takanori et al.

OCTA visualized lamina cribrosa microvasculature, showing reduced flow in glaucoma. This novel imaging may help identify and understand glaucoma-related LC changes.

Nakanishi Hideo, Suda Kenji, Yoshikawa Munemitsu, Akagi Tadamichi, Kameda Takanori, Ikeda Hanako Ohashi et al.

This study found optic disc ovality linked to axial length and visual field loss in glaucoma, highlighting how eye shape influences disc assessment and disease progression.

Shimazaki Takeru, Hirooka Kazuyuki, Nakano Yuki, Nitta Eri, Ukegawa Kaori, Tsujikawa Akitaka

This study found higher retinal venous oxygen saturation in worse visual field areas, particularly in normal-tension glaucoma, suggesting impaired oxygen extraction in affected regions.

Dodo Yoko, Murakami Tomoaki, Suzuma Kiyoshi, Yoshitake Shin, Yoshitake Tatsuya, Ishihara Kenji et al.

This study found specific neuroglial damage on OCT corresponds to superficial and deep capillary nonperfusion areas in diabetic retinopathy, enabling layer-by-layer assessment of retinal health.

Kobayashi Mamoru, Hirooka Kazuyuki, Ono Aoi, Nakano Yuki, Nishiyama Akira, Tsujikawa Akitaka

This study found RAAS and NMDA pathways cause retinal ganglion cell death independently. Spironolactone protected against aldosterone-induced damage, and memantine against NMDA-induced damage, suggesting distinct mechanisms for RGC neuroprotection.

Hata Masayuki, Yamashiro Kenji, Ooto Sotaro, Oishi Akio, Tamura Hiroshi, Miyata Manabu et al.

This study found pachychoroid neovasculopathy has lower intraocular VEGF than nAMD, suggesting different angiogenesis mechanisms. Lower VEGF predicted better anti-VEGF response in PNV, guiding treatment expectations.

Nitta Eri, Hirooka Kazuyuki, Shimazaki Takeru, Sato Shino, Ukegawa Kaori, Nakano Yuki et al.

Glaucoma surgery significantly lowered IOP, increasing retinal venous oxygen saturation, suggesting improved retinal blood flow and oxygenation, potentially benefiting optic nerve health.

Hirooka Kazuyuki, Sato Shino, Nitta Eri, Tsujikawa Akitaka

This study found that a glaucoma patient's visual field index (VFI) in their worse eye best correlates with vision-related quality of life, offering a useful clinical assessment tool.

Shimazaki Takeru, Hirooka Kazuyuki, Nakano Yuki, Nitta Eri, Ukegawa Kaori, Sato Shino et al.

Glaucoma patients with worse visual field defects showed higher retinal venous oxygen saturation, suggesting reduced oxygen extraction due to ganglion cell loss, which may indicate metabolic dysfunction.

Muraoka Yuki, Tsujikawa Akitaka, Hata Masayuki, Yamashiro Kenji, Ellabban Abdallah A, Takahashi Ayako et al.

This study found paravascular inner retinal defects (PIRDs) are common in high myopia or with epiretinal membranes, often causing corresponding visual field loss. This highlights the functional impact of these retinal changes.

Ooto Sotaro, Ellabban Abdallah A, Ueda-Arakawa Naoko, Oishi Akio, Tamura Hiroshi, Yamashiro Kenji et al.

This study found reticular pseudodrusen (RPD) are associated with reduced retinal sensitivity, best detected by infrared imaging. This suggests RPD, a common AMD precursor, functionally impairs the retina.