Nakanishi Hideo

Akagi Tadamichi, Uji Akihito, Okamoto Yoko, Suda Kenji, Kameda Takanori, Nakanishi Hideo et al.

AS-OCTA showed no overall vessel density difference in glaucoma eyes, but prostaglandin use and IOP affected superficial/deep vessel density, suggesting utility for assessing hyperemia and outflow pathophysiology.

Numa Shogo, Akagi Tadamichi, Uji Akihito, Suda Kenji, Nakanishi Hideo, Kameda Takanori et al.

OCTA visualized lamina cribrosa microvasculature, showing reduced flow in glaucoma. This novel imaging may help identify and understand glaucoma-related LC changes.

Nakanishi Hideo, Suda Kenji, Yoshikawa Munemitsu, Akagi Tadamichi, Kameda Takanori, Ikeda Hanako Ohashi et al.

This study found optic disc ovality linked to axial length and visual field loss in glaucoma, highlighting how eye shape influences disc assessment and disease progression.

Yoshikawa Munemitsu, Nakanishi Hideo, Yamashiro Kenji, Miyake Masahiro, Akagi Tadamichi, Gotoh Norimoto et al.

This study found the CDKN2B gene is linked to specific retinal nerve fiber layer thinning and corresponding paracentral/lower visual field defects in glaucoma, aiding detailed genetic risk assessment.

Hasegawa Tomoko, Ooto Sotaro, Takayama Kohei, Makiyama Yukiko, Akagi Tadamichi, Ikeda Hanako O et al.

This study found cone photoreceptor integrity (density, organization) was preserved in glaucoma patients, even with visual field loss, suggesting cones are resilient. This challenges assumptions about early cone damage.

Akagi Tadamichi, Iida Yuto, Nakanishi Hideo, Terada Noriko, Morooka Satoshi, Yamada Hiroshi et al.

Glaucoma patients with hemifield visual field defects showed region-specific microvascular reduction in the peripapillary retina and partially in the optic disc, correlating with visual field loss. This suggests microvascular changes contribute to glaucoma progression.

Nakanishi Hideo, Akagi Tadamichi, Suda Kenji, Hasegawa Tomoko, Yamada Hiroshi, Yokota Satoshi et al.

This study clustered combined visual field points and RNFL sectors in glaucoma, finding significant correlations that support the function-structure relationship, aiding understanding of glaucomatous damage patterns.

Nakanishi Hideo, Akagi Tadamichi, Hangai Masanori, Kimura Yugo, Suda Kenji, Hasegawa Tomoko et al.

Studying axial length's effect on mGCC thickness and glaucoma diagnosis, researchers found axial length impacts mGCC, and current SD-OCT normative databases misdiagnose highly myopic eyes, even with magnification correction.

Akagi Tadamichi, Nakano Eri, Nakanishi Hideo, Uji Akihito, Yoshimura Nagahisa

This study found ciliochoroidal detachment is common after ab interno trabeculotomy, causing transient low IOP, likely due to increased uveoscleral outflow. This explains early postoperative hypotony.

Yamada Hiroshi, Akagi Tadamichi, Nakanishi Hideo, Ikeda Hanako O, Kimura Yugo, Suda Kenji et al.

This study found that peripapillary atrophy with Bruch's membrane (PPA+BM) is linked to faster visual field progression in glaucoma, while PPA without Bruch's membrane (PPA-BM) may be protective. This microstructure helps predict glaucoma worsening.

Hasegawa Tomoko, Akagi Tadamichi, Hangai Masanori, Yamada Hiroshi, Suda Kenji, Kimura Yugo et al.

This study found that in glaucomatous eyes, the deep scleral opening is nasally shifted from Bruch's membrane opening, correlating with disc tilt and axial length. This informs glaucoma assessment, especially in myopic, tilted discs.

Suda Kenji, Hangai Masanori, Akagi Tadamichi, Noma Hisashi, Kimura Yugo, Hasegawa Tomoko et al.

This study found functional (SAP) and structural (OCT) glaucoma tests detect progression differently, highlighting their complementary roles in monitoring optic nerve damage over time.

Nakanishi Hideo, Akagi Tadamichi, Hangai Masanori, Kimura Yugo, Suda Kenji, Kumagai Kyoko Kawashima et al.

Studying highly myopic eyes, a myopic normative database for mGCC thickness significantly improved specificity for early glaucoma detection, reducing false positives compared to a non-myopic database.

Muraoka Yuki, Tsujikawa Akitaka, Hata Masayuki, Yamashiro Kenji, Ellabban Abdallah A, Takahashi Ayako et al.

This study found paravascular inner retinal defects (PIRDs) are common in high myopia or with epiretinal membranes, often causing corresponding visual field loss. This highlights the functional impact of these retinal changes.

Nakano Noriko, Hangai Masanori, Nakanishi Hideo, Mori Satoshi, Nukada Masayuki, Kotera Yuriko et al.

Speckle noise-reduced SD-OCT clearly showed macular GCL thinning in preperimetric glaucoma, especially inferiorly. This method offers high sensitivity for early glaucoma detection, improving diagnosis before vision loss.

Nukada Masayuki, Hangai Masanori, Mori Satoshi, Nakano Noriko, Nakanishi Hideo, Ohashi-Ikeda Hanako et al.

Enhanced SD-OCT, with speckle noise reduction, improved detection of localized retinal nerve fiber layer defects in glaucoma compared to other OCTs, offering better diagnostic sensitivity and specificity.

Sakamoto Atsushi, Hangai Masanori, Nukada Masayuki, Nakanishi Hideo, Mori Satoshi, Kotera Yuriko et al.

3D SD-OCT effectively detects macular RNFL defects in glaucoma, revealing more defects than fundus photos, especially in tessellated fundi, improving defect identification and severity assessment.

Nakano Noriko, Hangai Masanori, Nakanishi Hideo, Inoue Ryo, Unoki Noriyuki, Hirose Fumitaka et al.

Early AS-OCT bleb wall reflectivity (uniform vs. multiform) two weeks post-trabeculectomy predicts 6-month bleb function, with multiform blebs (showing multiple layers/microcysts) indicating better outcomes.

Inoue Ryo, Hangai Masanori, Kotera Yuriko, Nakanishi Hideo, Mori Satoshi, Morishita Shiho et al.

3D OCT showed glaucoma patients' lamina cribrosa thickness correlated significantly with visual field loss, offering a non-invasive way to assess structural damage.

Hayashi Hisako, Gotoh Norimoto, Ueda Yoshiki, Nakanishi Hideo, Yoshimura Nagahisa

This study found LOXL1 gene SNPs are strongly associated with Exfoliation Syndrome in Japanese patients, but with different risk alleles/haplotypes than Caucasians, suggesting population-specific genetic risk factors.