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Subconjunctival Administration of an Adeno-Associated Virus Expressing Stanniocalcin-1 Provides Sustained Intraocular Pressure Reduction in Mice.
Roddy Gavin W, Kohli Darrell, Niknam Parvin, Omer Mohammed E, Chowdhury Uttio Roy, Anderson Kjersten J et al.
Ophthalmol SciJul 20241 citationsBasic Science
Subconjunctival gene therapy (AAV-STC-1) significantly lowered intraocular pressure in mice for weeks, offering a potential sustained glaucoma treatment with fewer side effects than daily drops.