Pepple Kathryn L

Jabs Douglas A, Sugar Elizabeth A, Burke Alyce E, Altaweel Michael M, Dunn James P, Gangaputra Sapna et al.

Uveitis patients on systemic therapy face high, ongoing cataract surgery risk, especially with age or topical steroids. Surgery generally yields good visual outcomes, but risk factors need careful monitoring.

Pepple Kathryn L, Wilson Leslie, Van Gelder Russell N

This study compared immune cells in two rat uveitis models, finding distinct T-cell and B-cell profiles. This helps refine models for testing new uveitis therapies.

Gutowski Michal B, Wilson Leslie, Van Gelder Russell N, Pepple Kathryn L

Bioluminescence imaging effectively quantified intraocular inflammation in mouse uveitis models, especially acute anterior forms. This non-invasive method offers a valuable tool for monitoring inflammation in ophthalmic research.

Pepple Kathryn L, Rotkis Lauren, Wilson Leslie, Sandt Angela, Van Gelder Russell N

This study identified S100A8/A9 and apolipoprotein E as elevated in rat uveitis models, while neuroprotective β-B2-crystallin decreased in EAU, suggesting potential therapeutic targets for ocular inflammation.