Qing Guoping

Li Qian, Pu Liping, Cheng Sijie, Tang Shaoping, Zhang Jingxue, Qing Guoping

Pigment dispersion in glaucoma mice enhances ocular immune privilege by increasing immunosuppressive factors and regulatory T cells, potentially protecting the eye from inflammation.

Pu Liping, Zhou Rongyao, Li Qian, Qing Guoping

DBA/2J mouse studies found larger, more abundant pigment particles (>0.4 µm) in the trabecular meshwork correlated with higher intraocular pressure. This suggests pigment size and quantity contribute to outflow obstruction in pigmentary glaucoma.

Zhang Shaodan, Wang Bo, Xie Yuan, Zhu SenHua, Thomas Ravi, Qing Guoping et al.

Advanced glaucoma patients show reduced gray matter volume and cerebral blood flow in the primary visual cortex, worsening with disease severity. This suggests brain involvement in glaucoma and potential CBF biomarkers.

Qing Guoping, Wang Ningli, Wang Huaizhou

Qing Guoping, Zhang Shaodan, Wang Bo, Wang Ningli

fMRI in glaucoma patients with normal central vision showed reduced visual cortex activity in the more affected eye, linked to visual field damage (PSD), not structural measures.