Wang Ningli

Wang Jin, Hu Keyu, Liu Zijian, Zhang Ye, Mou Dapeng, Wang Ningli

This study found lens-related angle-closure glaucoma patients had higher 5-year reoperation rates after Phaco-GSL than primary angle-closure, emphasizing tailored management for these high-risk individuals.

Wang Jin, Wang Yue, Liu Zijian, Mou Dapeng, Tang Xin, Shi Danli et al.

APAC eyes show persistent retinal vasculometric changes (larger veins, altered fractal dimension/AV ratio) even after IOP control. These may be independent APAC risk factors, offering post-APAC monitoring via standard fundus photography.

Song Qian-Qian, Xu Wenjun, Li Shi-Ming, Wang Ningli, Kang Meng-Tian

Repeated supraclinical red laser exposure damaged guinea pig retina (photoreceptors, RPE) via apoptosis, identifying vulnerable fundus targets, but spared anterior structures.

Wan Yue, Liu Xiangxiang, Yan Xuejing, Wu Shen, Teng Yufei, Han Luyi et al.

AAV-DJ-shMYOC gene therapy reduced mutant myocilin, preventing IOP elevation, preserving RGCs and visual function in young mice. It also lowered IOP in aged mice, showing potential for myocilin-related glaucoma by targeting the underlying proteinopathy.

Li Jiaying, Zhang Ye, Cheng Zhen, Qiao Chunyan, Cao Kai, He Minguang et al.

This study found that specific AS-OCT angle parameters, particularly those closer to the scleral spur, are better screening indicators for progressive primary angle closure glaucoma than for non-progressive angle closure disease, guiding targeted screening.

Liu Hongyi, Hou Simeng, Zhu Sirui, Liu Weihai, Regmi Moksada, Yang Chenlong et al.

This study established normal macular thickness in cynomolgus monkeys, finding associations with age, axial length, and IOP. This provides crucial reference data for preclinical glaucoma research.

Wang Jin, Wang Yue, Zhang Ye, Tang Xin, Wang Dabo, Wang Ningli et al.

This study found non-pupillary block PACD mechanisms lead to more postoperative PAS after surgery, highlighting the need for detailed preoperative assessment to optimize long-term outcomes.

Wan Yue, Guo Xinzheng, Wang Ningli

The trabecular meshwork's dysfunction is central to glaucoma's elevated eye pressure. New therapies, from drugs to gene and cell-based approaches, are targeting the TM to restore function and improve glaucoma treatment.

Wang Jin, Han Shumei, Mou Dapeng, Tang Xin, Shi Danli, He Mingguang et al.

Retinal vascular changes distinguish primary angle-closure glaucoma from earlier stages and are independently linked to optic nerve damage, potentially offering new biomarkers for disease progression.

Han Luyi, Mao Yingyan, Sang Qing, Wan Yue, Wang Ningli

This study found microcatheter-assisted MIGS, specifically MAT, is as effective as trabeculectomy with MMC for IOP and medication reduction in open-angle glaucoma, with some MIGS offering complication advantages.

Pan Lijie, Wang Ningli, Wu Jian

This review highlights NHPs as ideal models for optic nerve research, including glaucoma. Their human-like physiology and the NHPES study provide crucial insights, accelerating novel treatment development and improving patient outcomes.

Mou Dapeng, Wang Jin, Zhang Ye, Wang Yue, Tang Xin, Wang Ningli

This study found tailored phacoemulsification-glaucoma surgeries, guided by axial length, effectively and safely controlled IOP in nanophthalmos with angle closure, reducing complications.

Wang Jin, Liu Tingting, Li Sizhen, He Mingguang, Wang Xiaofei, Wang Ningli et al.

This study found iris changes with age and sex in healthy Chinese individuals, with older age and female sex linked to smaller iris area changes, potentially explaining higher angle-closure glaucoma prevalence.

Ye Wenqing, Li Jinxing, Zhang Shaodan, Zhu Shuqing, Xie Yanqian, Le Rongrong et al.

This study compared two canaloplasty techniques for glaucoma, finding penetrating canaloplasty achieved superior IOP reduction and success rates with similar safety, suggesting it's a more effective surgical option.

Mou Dapeng, Wang Jin, Wang Huaizhou, Wang Ningli

This study compared Phaco-KDB and Phaco-Trabectome for open-angle glaucoma. Both surgeries significantly reduced IOP and medication use with similar effectiveness, offering comparable options for patients.

Pang Ruiqi, Peng Jieting, Cao Kai, Sun Yunxiao, Pei Xue-Ting, Yang Diya et al.

This study found that impaired contrast sensitivity, particularly at low spatial frequencies, correlates with structural damage in glaucoma, suggesting it's a valuable measure of disease severity.

Chen De-Fu, Wang Chenmin, Si Yuqing, Lu Xiaonan, Zhou Weihe, Huang Qiangjie et al.

Nearly two-thirds of untreated Chinese NTG patients progressed. Disc hemorrhage, female gender, higher IOP, shorter axial length, and lower diastolic BP predicted progression, highlighting key risk factors for clinical management.

Wang Jin, Wang Yue, Zhang Qing, Li Si Zhen, He Ming Guang, Wang Ningli et al.

This study found that dynamic and static iris parameters are consistent across primary angle-closure disease patients, regardless of axial length, suggesting these factors contribute to angle closure even in atypical cases.

Pang Ruiqi, Peng Jieting, Zhang Qing, Cao Kai, Lu Zhong-Lin, Wang Ningli

This study found macular GC/IPL thinning correlates with contrast sensitivity impairment in early-advanced glaucoma, but not pre-perimetric, suggesting its utility for severity assessment.

Lei Kun, Tang Yang, Pang Ruiqi, Zhou Huiying, Yang Liu, Wang Ningli

This study compared retinal microvasculature in compressive versus glaucomatous optic neuropathy. Key finding: compressive neuropathy showed less retinal vascular impairment than glaucoma, despite similar structural damage. This aids differentiation.

Zhang Hui, Zhang Ye, Zhang Shuo, Cao Kai, Li Dongjun, Liu Mugen et al.

This study found zonulopathy is common in primary angle closure disease, especially acute angle closure, linked to shallow anterior chambers and thick lenses. Clinically, this highlights surgical risks in these patients.

Liang Yuanbo, Shen Ruyue, Zhou Weihe, Fan Sujie, Chan Poemen P, Tham Clement C Y et al.

This study found myopia is common in younger Chinese patients with primary angle closure disease (PACD) and over half with primary angle closure glaucoma (PACG) are myopic, despite typical PACD eyes being shorter. This highlights myopia's prevalence even in eyes predisposed to angle closure.

Li Ruyue, Wang Ningli, Liu Hanruo

Pang Ruiqi, Labisi Siloka A, Wang Ningli

This review highlights racial differences in PDS/PG prevalence, presentation, and conversion rates, emphasizing tailored diagnosis and treatment for diverse patient populations.

Zhang Yue, Cao Kai, Pang Ruiqi, Wang Ning, Qu Xin, Kang Jun et al.

This study found that ultrasound measurement of the optic nerve subarachnoid space area (ONSASA) accurately estimates intracranial pressure (ICP) using a formula, offering a rapid, non-invasive clinical tool.