Yang Diya

Xie Yuan, Sun Yunxiao, Shao Yaqi, Tian Jiaxing, Fu Yingdi, Yang Diya et al.

Simulated high altitude caused pupil miosis and anterior chamber angle widening. This suggests high altitude exposure might be safe for individuals with narrow angles, warranting further study.

Pang Ruiqi, Peng Jieting, Cao Kai, Sun Yunxiao, Pei Xue-Ting, Yang Diya et al.

This study found that impaired contrast sensitivity, particularly at low spatial frequencies, correlates with structural damage in glaucoma, suggesting it's a valuable measure of disease severity.

El-Nimri Nevin W, Moghimi Sasan, Penteado Rafaella C, Ghahari Elham, Yang Diya, Brye Nicole et al.

LBN significantly increased macular blood vessel density in glaucoma/OHT patients, unlike timolol, suggesting LBN may offer superior retinal perfusion benefits beyond IOP reduction.

Ekici Eren, Moghimi Sasan, Bowd Christopher, Hou Huiyuan, Penteado Rafaella C, Proudfoot James et al.

OCTA vessel density differs among glaucoma optic disc phenotypes, with senile sclerotic discs having lowest density. Clinically, OCTA's diagnostic accuracy for glaucoma varies by disc phenotype.

Yang Diya, Liu John H K, Wang Ningli, Weinreb Robert N

This study found prostaglandin analogs weaken the correlation between office-hour and peak nocturnal IOP, suggesting office readings may be less reliable for assessing peak IOP under treatment.

Hou Huiyuan, Moghimi Sasan, Proudfoot James A, Ghahari Elham, Penteado Rafaella C, Bowd Christopher et al.

This study found that in primary open-angle glaucoma, macular vessel density loss occurs faster than ganglion cell thinning and correlates with disease severity, making it useful for monitoring progression.

Liu Xiangxiang, Yang Diya, Yang Yiquan, Liu Hanruo, Li Xiaoxia, Xie Yuan et al.

Xie Xiaobin, Chen Weiwei, Li Zhen, Thomas Ravi, Li Yong, Xian Junfang et al.

This study found ocular hypertensive patients have higher orbital CSF pressure, but their trans-lamina cribrosa pressure difference is still significantly higher, potentially increasing glaucoma risk.

Liu Hanruo, Yang Diya, Ma Teng, Shi Wenyuan, Zhu Qiang, Kang Jun et al.

This study found optic nerve subarachnoid space area is significantly smaller in normal tension glaucoma than in POAG or controls, suggesting lower CSF pressure and potentially higher trans-lamina cribrosa pressure difference in NTG.

Huang Alex S, Li Meng, Yang Diya, Wang Huaizhou, Wang Ningli, Weinreb Robert N

Aqueous angiography in living nonhuman primates revealed dynamic, segmental, and pulsatile outflow patterns, improving understanding of aqueous humor biology and potentially guiding glaucoma surgeries.

Jonas Jost B, Wang Ningli, Yang Diya

This study suggests glaucoma isn't just high eye pressure; low orbital cerebrospinal fluid pressure creates a critical pressure difference across the optic nerve, potentially causing damage even with normal eye pressure.

Zhang Zheng, Liu Danli, Jonas Jost B, Wu Shen, Kwong Jacky M K, Zhang Jingxue et al.

Zhang Zheng, Liu Danli, Jonas Jost B, Wu Shen, Kwong Jacky M K, Zhang Jingxue et al.

Both short-term low CSFP and high IOP disrupted axonal transport in rats. This suggests abnormally low CSFP, like high IOP, can harm the optic nerve, impacting glaucoma understanding.

Zhang Zheng, Wang Xiaolei, Jonas Jost B, Wang Huaizhou, Zhang Xiaojun, Peng Xiaoxia et al.

Jonas Jost B, Wang Ningli, Yang Diya, Ritch Robert, Panda-Jonas Songhomitra

Orbital cerebrospinal fluid pressure (CSFP) influences trans-lamina cribrosa pressure, choroidal thickness, and retinal venous pressure. Abnormal CSFP, particularly relative to IOP, may contribute to glaucoma and other retinopathies.

Zhang Zheng, Wang Xiaolei, Jonas Jost B, Wang Huaizhou, Zhang Xiaojun, Peng Xiaoxia et al.

Valsalva maneuver increases CSF-P more than IOP, transiently reversing trans-laminar pressure difference, altering optic nerve head shape. This suggests mechanical stress on the optic nerve is complex and relevant to glaucoma.

Wang Ningli, Yang Diya, Jonas Jost B

This study questions if low cerebrospinal fluid pressure causes primary open-angle glaucoma, finding significant overlap in lumbar CSFP between glaucoma patients and healthy individuals, suggesting other factors are crucial.

Jonas Jost B, Yang Diya, Wang Ningli

This study links low cerebrospinal fluid pressure (CSFP) to glaucoma, especially normal-tension type. It suggests CSFP, not just IOP, impacts optic nerve damage, highlighting a new therapeutic target.

Wang Ningli, Xie Xiaobin, Yang Diya, Xian Junfang, Li Yong, Ren Ruojin et al.

This study found normal-pressure glaucoma patients have a significantly narrower optic nerve subarachnoid space, suggesting lower orbital CSF pressure contributes to this glaucoma type.

Jonas Jost B, Wang Ningli, Yang Diya

Zhang Zheng, Yang Diya, Sang Jinhong, Hou Ruowu, Liu Kegao, Li Zhen et al.

This study found high reproducibility of OCT measurements (RNFL, ONH, MIRL) in Rhesus monkeys, suggesting its reliability for monitoring experimental glaucoma progression in these models.