Liang Yuanbo

Zheng Xuanli, Zhao Fengping, Chen Huan, Lin Haishuang, Li Jiaqian, Zhang Junfan et al.

This rabbit study shows ciliary block-induced trans-lens pressure difference drives anterior chamber shallowing, angle closure, and high IOP, providing a valuable model to understand human angle-closure glaucoma.

You Ruirong, Zhou Xingyu, Xu Xiaowei, Wang Wenjing, Yu Daokuan, Fang Xinyi et al.

Flicker stimulation showed impaired retinal microvascular response in normal-tension glaucoma eyes compared to high-tension glaucoma and healthy eyes, suggesting distinct vascular pathophysiology and potential diagnostic differences.

Shen Ru Yue, Zhang Yuqiao, Chen Li Jia, Cheung Carol Y, Liang Yuanbo, Tham Clement C et al.

This review synthesized evidence on glaucoma risk factors, finding strong links for IOP, myopia, corneal hysteresis, and total antioxidant status, guiding future research and clinical risk assessment.

Chen De-Fu, Zhou Wenzhe, Lu Xiaonan, Wang Tao, Wang Chenmin, Wang Yaoyao et al.

MRF, a web-browser visual field test, proved reliable and faster than HFA for Chinese glaucoma patients, offering an accessible, efficient alternative to improve care, especially in underserved areas.

Lu Xiaonan, Chen De-Fu, Wang Chenmin, Zhang Jinrui, Wang Tao, Zhang Cong et al.

This study found hemiretinal asymmetry in vessel density and nerve fiber layers increases with normal tension glaucoma progression, aiding early diagnosis and staging, especially differentiating pre-perimetric and early stages.

Liang Yuanbo, Yu Yun, Wen Xin, Wang Mei, Lan Yuqing, Pan Xiafei

This study found POAG patients walking over 10,000 steps daily had higher optic disc vessel density, suggesting increased physical activity might improve ocular blood flow and potentially benefit glaucoma management.

Xu Lijuan, Zhao Yin, Zhang Xinyao, Gang Xiaorui, Han Jialing, Zhou Tao et al.

Sustained low intraocular pressure in rats induced TM and SC fibrosis, potentially impairing aqueous humor outflow. Clinicians should consider this outflow channel damage from IOP fluctuations.

Ye Wenqing, Li Jinxing, Zhang Shaodan, Zhu Shuqing, Xie Yanqian, Le Rongrong et al.

This study compared two canaloplasty techniques for glaucoma, finding penetrating canaloplasty achieved superior IOP reduction and success rates with similar safety, suggesting it's a more effective surgical option.

Xiong Kun, Zhang Qi'ao, Mao Huiyan, Congdon Nathan, Liang Yuanbo

This study found no causal link between six diet-derived antioxidants and primary open-angle glaucoma or related traits, suggesting antioxidant intake likely doesn't prevent glaucoma or protect retinal nerve cells.

Lin Sigeng, Shang Xiao, Wang Xiaoyan, Chu Xizhong, Hu Chengju, Si Yuqing et al.

This study found that decreased macular deep capillary plexus (DCP) density predicts future visual field loss in the unaffected eye of normal tension glaucoma patients, offering a new risk assessment tool.

Lin Sigeng, Zhang Shaodan, Shang Xiao, Gu Juan, Ye Cong, Wang Xiaoyan et al.

Glaucoma patients with one-sided visual field loss showed faster macular vessel density decline in the affected area, correlating with visual field damage severity, even without significant tissue thinning. This suggests mVD loss is an early, measurable glaucoma progression marker.

Liang Yuanbo, Shen Ruyue, Zhou Weihe, Fan Sujie, Chan Poemen P, Tham Clement C Y et al.

This study found myopia is common in younger Chinese patients with primary angle closure disease (PACD) and over half with primary angle closure glaucoma (PACG) are myopic, despite typical PACD eyes being shorter. This highlights myopia's prevalence even in eyes predisposed to angle closure.

Xie Yanqian, Jiang Junhong, Liu Chi, Lin Haishuang, Wang Lin, Zhang Cong et al.

Health center glaucoma screening effectively detects early-stage disease, including normal-tension glaucoma, with less visual impairment than clinic detection, improving early intervention.

Nie Li, Cheng Dan, Cen Jiner, Ye Yufeng, Qiao Yilin, Fang Jia et al.

Moderate exercise increased macular blood flow in glaucoma patients without significant optic nerve changes, and temporarily lowered IOP in both groups, suggesting potential ocular benefits warranting further study.

Wei Liqing, Fu Lin, Nie Li, Lian Hengli, Qian Zhenbin, Liang Yuanbo et al.

Phaco-GSL effectively lowers IOP in angle-closure glaucoma regardless of initial PAS extent, but larger PAS requires more intraoperative separation and has higher recurrence.

Ye Cong, Wang Xiaoyan, Yu Marco Chak-Yan, Shang Xiao, Zhou Kun, Tao Yan et al.

This study found macular vessel density, ganglion cell thickness, and nerve fiber layer all decrease in POAG, but their progression detection poorly agrees. Baseline metrics influenced vessel density loss.

Zhang Shaodan, Sun Jing, Liu Shanshan, Liang Yuanbo, Hu Ying, Congdon Nathan et al.

Integrating glaucoma screening into general health exams in China identified suspects affordably, showing promise for early detection, but follow-up rates for further evaluation need improvement.

Lin Sigeng, Cheng Huanhuan, Zhang Shaodan, Ye Cong, Pan Xiafei, Tao Aizhu et al.

This study found that parapapillary microvasculature dropout (MvD) predicts faster retinal nerve fiber layer (RNFL) thinning in normal-tension glaucoma, highlighting MvD as a key indicator of disease progression.

Liang Yuanbo, Jiang Junhong, Ou Wen, Peng Xianyao, Sun Ruizhu, Xu Xiang et al.

Community screening identified glaucoma patients with significantly milder disease and more underserved demographics (older, female) than clinic-diagnosed cases, suggesting screening improves early detection, especially for normal-tension glaucoma.

Zhang Shaodan, Liang Yuanbo, Chen Yanyun, Musch David C, Zhang Chun, Wang Ningli

This study found glaucoma significantly reduces patient quality of life. Ophthalmologists underestimated the impact of mild glaucoma, highlighting the need for better understanding patient perspectives for shared decision-making.

Tham Clement C Y, Leung Dexter Y L, Kwong Yolanda Y Y, Liang Yuanbo, Peng Andrea Yi, Li Felix C H et al.

In PACG eyes with cataract, high preoperative IOP and more glaucoma drugs predict IOP control failure. Phacotrabeculectomy is superior to phacoemulsification alone for IOP control.

Lin Zhong, Liang Yuanbo, Wang Ningli, Li Sizhen, Mou Dapeng, Fan Sujie et al.

This study found peripheral anterior synechiae (PAS) limit angle widening after LPI in primary angle closure. This means LPI is less effective in areas with existing PAS.

Liang Yuanbo, Friedman David S, Zhou Qiang, Yang Xiao Hui, Sun Lan Ping, Guo Lixia et al.

This study found primary angle-closure glaucoma (0.5%), PAC (1.5%), and PACS (10.4%) in rural Chinese adults, increasing with age and higher in females. Many with PACG were blind, highlighting the need for early detection.