Li Si Zhen

Wang Jin, Wang Yue, Zhang Qing, Li Si Zhen, He Ming Guang, Wang Ningli et al.

This study found that dynamic and static iris parameters are consistent across primary angle-closure disease patients, regardless of axial length, suggesting these factors contribute to angle closure even in atypical cases.

Zhang Ye, Zhang Qing, Li Si Zhen, He Ming Guang, Li Shu Ning, Wang Ning Li

This study found primary angle closure disease (PACD) is rare in long eyes, characterized by a thicker peripheral iris, larger lens vault, and smaller anterior chamber width, offering insights into its unique mechanisms.

Zhang Ye, Hao Jie, Zhang Qing, Wang Jin, Li Si Zhen, Thomas Ravi et al.

This study found a 1.6% 5-year glaucoma incidence in rural China. Older age, higher IOP, and larger cup-to-disc ratio are key risk factors, helping identify high-risk individuals for early intervention.

Zhang Ye, Zhang Qing, Thomas Ravi, Li Si Zhen, Wang Ning Li

This study found high triglycerides independently increased glaucoma risk in rural Chinese adults, suggesting metabolic factors are involved in glaucoma's development.

Zhang Ye, Thomas Ravi, Zhang Qing, Li Si Zhen, Wang Ning Li

This study found 32/526 primary angle closure suspects progressed to angle closure/glaucoma over five years in rural Chinese adults, with narrower baseline angle width being the key predictive risk factor.

Zhang Ye, Zhang Qing, Thomas Ravi, Li Si Zhen, Wang Ning Li

This study found that shallower anterior chamber depth and narrower angle width predict the development of angle closure from an open angle in a rural Chinese population, highlighting key risk factors for progression.

Zhang Ye, Dong Zhe, Zhang Qing, Li Lei, Thomas Ravi, Li Si Zhen et al.

Prediction models using ASOCT effectively detect primary angle-closure suspects, performing best for pupillary block mechanisms, offering potential for improved screening of this glaucoma risk.

Zhang Ye, Zhang Qing, Li Lei, Thomas Ravi, Li Si Zhen, He Ming Guang et al.

Algorithms combining ASOCT parameters to detect primary angle closure suspects were evaluated. They did not meet population screening requirements, highlighting the complexity of angle closure mechanisms, but advance image-based screening research.

Wang Ning Li, Hao Jie, Zhen Yi, Liu John H K, Li Si Zhen, Wang Hao et al.

This study found healthy individuals have significant IOP fluctuations (7.0 mmHg median peak-trough difference) over 24 hours, often peaking nocturnally. This highlights the importance of 24-hour IOP monitoring for glaucoma management.

Zhang Ye, Li Si Zhen, Li Lei, He Ming Guang, Thomas Ravi, Wang Ning Li

This study found dynamic iris changes, specifically less iris area loss during pupil dilation, are a risk factor for primary angle closure disease, highlighting its role in disease development.

Zhang Ye, Li Si Zhen, Li Lei, He Ming Guang, Thomas Ravi, Wang Ning Li

This study found iris area changes after dilation differ significantly among angle closure mechanisms; pupillary block eyes showed the least change, suggesting dynamic iris behavior is crucial in this type.

Sun Xia, Liang Yuan Bo, Wang Ning Li, Fan Su Jie, Sun Lan Ping, Li Si Zhen et al.

This study found LPI alone or with iridoplasty similarly reduces IOP in angle-closure glaucoma, but iridoplasty may further reduce synechiae, offering a potential adjunct benefit.