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Roy-Gagnon Marie-Hélène

7 articles in GJC

7 articles in GJC

1.

Retinal Vessel Traits and Age-Related Eye Disease in the Canadian Longitudinal Study on Aging.

O'Neil Alexis, Welikala Roshan A, Barman Sarah, Owen Christopher G, Rudnicka Alicja R, Rakesh Mohan et al.

Clin Exp OphthalmolJun 20253 citationsLongitudinal Study

This study found wider retinal arterioles linked to lower glaucoma odds, but glaucoma itself narrowed arterioles over time. Wider venules predicted higher AMD risk, highlighting microvascular changes as potential disease markers.

2.

Does the Association Between Eye Disease and Cognitive Function Vary by Genetic Risk of Cognitive Decline? An Analysis of Hospital Data With Replication in the Canadian Longitudinal Study on Aging.

Tran Emily, Rakesh Mohan, Li Gisele, Freeman Ellen E, Roy-Gagnon Marie-Hélène

Invest Ophthalmol Vis SciJun 20250 citationsCross-Sectional Study

This study found specific genes (KIBRA, PDE7A/MTFR1) may modify the link between eye diseases like glaucoma/AMD and cognitive function, suggesting a genetic influence on this complex relationship.

6.

Age-Related Eye Disease and Cognitive Function: The Search for Mediators.

Varin Mélanie, Kergoat Marie-Jeanne, Belleville Sylvie, Li Gisele, Rousseau Jacqueline, Roy-Gagnon Marie-Hélène et al.

OphthalmologyOct 201927 citationsCross-Sectional Study

This study found glaucoma patients scored lower on verbal working memory and encoding tests. Reduced activity levels partially mediated this link, suggesting interventions for visually impaired individuals could slow cognitive decline.

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