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Freeman Ellen E

16 articles in GJC

16 articles in GJC

1.

Retinal Vessel Traits and Age-Related Eye Disease in the Canadian Longitudinal Study on Aging.

O'Neil Alexis, Welikala Roshan A, Barman Sarah, Owen Christopher G, Rudnicka Alicja R, Rakesh Mohan et al.

Clin Exp OphthalmolJun 20253 citationsLongitudinal Study

This study found wider retinal arterioles linked to lower glaucoma odds, but glaucoma itself narrowed arterioles over time. Wider venules predicted higher AMD risk, highlighting microvascular changes as potential disease markers.

2.

Does the Association Between Eye Disease and Cognitive Function Vary by Genetic Risk of Cognitive Decline? An Analysis of Hospital Data With Replication in the Canadian Longitudinal Study on Aging.

Tran Emily, Rakesh Mohan, Li Gisele, Freeman Ellen E, Roy-Gagnon Marie-Hélène

Invest Ophthalmol Vis SciJun 20250 citationsCross-Sectional Study

This study found specific genes (KIBRA, PDE7A/MTFR1) may modify the link between eye diseases like glaucoma/AMD and cognitive function, suggesting a genetic influence on this complex relationship.

8.

Fine Particulate Matter and Age-Related Eye Disease: The Canadian Longitudinal Study on Aging.

Grant Alyssa, Leung Gareth, Aubin Marie-Josée, Kergoat Marie-Jeanne, Li Gisèle, Freeman Ellen E

Invest Ophthalmol Vis SciAug 202149 citationsCohort Study

This study found increased fine particulate matter (PM2.5) exposure is associated with higher glaucoma risk and intraocular pressure, suggesting air quality may impact eye health and warranting further investigation for public health guidelines.

10.

Age-Related Eye Disease and Cognitive Function: The Search for Mediators.

Varin Mélanie, Kergoat Marie-Jeanne, Belleville Sylvie, Li Gisele, Rousseau Jacqueline, Roy-Gagnon Marie-Hélène et al.

OphthalmologyOct 201927 citationsCross-Sectional Study

This study found glaucoma patients scored lower on verbal working memory and encoding tests. Reduced activity levels partially mediated this link, suggesting interventions for visually impaired individuals could slow cognitive decline.

12.

Estimation of ocular rigidity in glaucoma using ocular pulse amplitude and pulsatile choroidal blood flow.

Wang Jing, Freeman Ellen E, Descovich Denise, Harasymowycz Paul J, Kamdeu Fansi Alvine, Li Gisele et al.

Invest Ophthalmol Vis SciMar 201342 citationsCase-Control Study

This study estimated ocular rigidity in glaucoma, OHT, and normal eyes. Glaucoma patients had the lowest rigidity, while OHT patients had the highest, suggesting a more compliant eye may increase glaucoma risk.

13.

Activity limitation due to a fear of falling in older adults with eye disease.

Wang Meng Ying, Rousseau Jacqueline, Boisjoly Hélène, Schmaltz Heidi, Kergoat Marie-Jeanne, Moghadaszadeh Solmaz et al.

Invest Ophthalmol Vis SciDec 201266 citationsCross-Sectional Study

Older adults with glaucoma, AMD, or Fuchs disease commonly limit activity due to fear of falling (40-50% vs. 16% of controls), especially due to reduced contrast sensitivity. This highlights a need to address fall risk and social isolation in these patients.

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