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The β4-Subunit of the Large-Conductance Potassium Ion Channel KCa1.1 Regulates Outflow Facility in Mice.
Bertrand Jacques A, Schicht Martin, Stamer W Daniel, Baker David, Sherwood Joseph M, Lütjen-Drecoll Elke et al.
Invest Ophthalmol Vis SciMar 202011 citationsBasic Science
This study found the β4-subunit of KCa1.1 channels significantly regulates aqueous humor outflow, suggesting targeting these channels could be a novel glaucoma treatment to lower intraocular pressure.