Sotozono Chie

Mieno Hiroki, Mori Kazuhiko, Kano Kiyoshi, Yoshii Kengo, Kazuo Kumiko, Ikeda Yoko et al.

PRESERFLO MicroShunt effectively lowered IOP and medication use in a large Japanese cohort. High preoperative medication use and prior cataract surgery were risk factors for failure, guiding patient selection.

Okada Yo, Mieno Hiroki, Ueno Morio, Yoshii Kengo, Mori Kazuhiko, Sotozono Chie

This study found nasal and temporal incisions for 180-degree transluminal trabeculotomy are equally effective for lowering IOP in glaucoma patients, simplifying surgical approach without compromising outcomes.

Watanabe Mako, Kitazawa Koji, Fukuoka Hideki, Wakimasu Koichi, Inatomi Tsutomu, Yoshii Kengo et al.

This study found male gender, prior anterior uveitis, and glaucoma history significantly increase cytomegalovirus corneal endotheliitis risk after transplant. Close follow-up is crucial, especially in the first year.

Ikushima Toru, Iwase Aiko, Araie Makoto, Murata Hiroshi, Ueno Morio, Mori Kazuhiko et al.

This study found ambient atmospheric pressure positively correlates with Goldmann applanation tonometer-measured IOP in normal eyes. Clinically, this impact on IOP is likely minimal for individuals.

Kitazawa Koji, Toda Munetoyo, Ueno Morio, Wakimasu Koichi, Tomioka Yasufumi, Uehara Asako et al.

This study found donor corneas with mature endothelial cells significantly improve long-term graft survival, even in glaucoma patients, suggesting better outcomes with careful donor selection.

Ueno Morio, Yoshii Kengo, Yamashita Tomoko, Sonomura Kazuhiro, Asada Kazuko, Ito Eiko et al.

This study found specific aqueous humor metabolites (e.g., HIB) and microRNAs (e.g., miR-34a-5p) interact, influencing corneal endothelial health. This interplay is crucial for maintaining corneal clarity in diseases like bullous keratopathy.

Kitazawa Koji, Sotozono Chie, Kinoshita Shigeru

This abstract reviews corneal cell therapies, highlighting that Rho-associated protein kinase inhibition significantly advances cultured corneal endothelial cells, enabling injection therapy for severe corneal epithelial and endothelial diseases.

Yamashita Tomoko, Asada Kazuko, Ueno Morio, Hiramoto Nao, Fujita Tomoko, Toda Munetoyo et al.

This study found that stressed corneal cells release miR-184 via extracellular vesicles, which helps prevent corneal endothelium degeneration. This suggests miR-184 could be a therapeutic target for corneal health.

Maruyama Yuko, Ikeda Yoko, Mori Kazuhiko, Yoshii Kengo, Ueno Morio, Yoshikawa Haruna et al.

Ripasudil eye drops cause transient corneal endothelial cell morphological changes, leading to inaccurate cell density readings by specular microscopy within 6 hours, emphasizing timing for accurate assessment.

Ikeda Yoko, Ueno Morio, Yoshii Kengo, Nakano Masakazu, Sotozono Chie, Kinoshita Shigeru et al.

Okumura Naoki, Matsumoto Daiki, Okazaki Yugo, Koizumi Noriko, Sotozono Chie, Kinoshita Shigeru et al.

This study found corneal endothelial cell density significantly decreases over time specifically near trabeculectomy blebs, suggesting the bleb's role in localized cell loss warrants further investigation.

Mori Kazuhiko, Nakano Masakazu, Tokuda Yuichi, Ikeda Yoko, Ueno Morio, Sotozono Chie et al.

Nakatsukasa Mina, Sotozono Chie, Shimbo Kazutaka, Ono Nobukazu, Miyano Hiroshi, Okano Akira et al.

Tear amino acid profiles, distinct from blood/aqueous humor, show specific decreases (e.g., taurine, arginine) in severe ocular surface disease, suggesting their role as biomarkers for ocular surface health.

Koizumi Noriko, Suzuki Takashi, Uno Toshihiko, Chihara Hidemi, Shiraishi Atsushi, Hara Yuko et al.

This study found cytomegalovirus (CMV) causes corneal endotheliitis, often with specific signs, responding well to early antiviral treatment. Clinicians should consider CMV in endotheliitis, even without systemic immunodeficiency.

Koizumi Noriko, Yamasaki Kenta, Kawasaki Satoshi, Sotozono Chie, Inatomi Tsutomu, Mochida Chikako et al.

This case found cytomegalovirus (CMV) DNA in aqueous humor from a non-immunodeficient patient with corneal endotheliitis, suggesting CMV can cause this condition in healthy individuals.