Vandewalle Evelien

Berteloot Sophie, Correia Barão Rafael, Abegão Pinto Luís, Vandewalle Evelien, Stalmans Ingeborg, Lemmens Sophie

This study compared Paul and Baerveldt glaucoma implants, finding both safe and effective at one year for uncontrolled glaucoma, with similar success rates and IOP reduction.

Marques Raquel Esteves, Sousa David Cordeiro, Vandewalle Evelien, Somers Alix, Melamed Shlomo, Nardi Marco et al.

Ultrasound cycloplasty for glaucoma increased corneal astigmatism, but its impact on overall refractive astigmatism was less significant, suggesting minimal visual effect.

Hemelings Ruben, Elen Bart, Barbosa-Breda João, Lemmens Sophie, Meire Maarten, Pourjavan Sayeh et al.

A deep learning model accurately detected glaucoma from fundus images (AUC 0.995, 98% sensitivity) using less data through active/transfer learning, offering efficient, explainable automated screening.

Bevers Claudia, Blanckaert Gauthier, Van Keer Karel, Fils Jean-François, Vandewalle Evelien, Stalmans Ingeborg

This study found automated kinetic perimetry (HFA3, Octopus 900 without reaction time vector) produces comparable V4e visual fields to Goldmann perimetry, suggesting they are promising clinical replacements.

Barbosa-Breda João, Abegão-Pinto Luis, Van Keer Karel, Jesus Danilo A, Lemmens Sophie, Vandewalle Evelien et al.

Glaucoma studies show vast inconsistency in defining blood pressure and ocular perfusion pressure, leading to significant data disparities. A standardized approach is crucial for accurate research and clinical insights.

Willekens Koen, Abegão Pinto Luìs, Lemmens Sophie, Bataillie Sophie, Somers Alix, Vandewalle Evelien et al.

This study found glaucoma patients experienced later-stage posterior vitreous detachment (PVD) at an older age than healthy individuals, suggesting PVD development may differ in glaucoma.

Barbosa-Breda João, Van Keer Karel, Abegão-Pinto Luis, Nassiri Vahid, Molenberghs Geert, Willekens Koen et al.

This study found normal-tension glaucoma patients have more vascular dysfunction. Combining conventional and advanced vascular tests better differentiates them from primary open-angle glaucoma, highlighting the role of non-IOP factors.

Van Bergen Tine, Zahn Grit, Caldirola Patrizia, Fsadni Mario, Caram-Lelham Ninus, Vandewalle Evelien et al.

This study found the integrin α5β1 inhibitor CLT-28643 improved glaucoma surgery outcomes in mice, potentially superior to MMC, by reducing wound healing and showing good tolerability.

Van Ginderdeuren Rita, Vandewalle Evelien, Pinto Luis Abegão, Stalmans Ingeborg, Zeyen Thierry

This study found normal tension glaucoma patients have significantly thinner conjunctiva than primary open-angle glaucoma patients, suggesting a systemic pattern of thinner ocular tissues in NTG.

Willekens Koen, Pinto Luìs A, Delbeke Heleen, Vandewalle Evelien, Stalmans Ingeborg

Trabeculectomy using a specific conjunctival closure technique (Moorfields) showed low complications and only a transient, reversible astigmatism shift, suggesting it's a safe technique that avoids permanent refractive changes.

Delbeke Heleen, Stalmans Ingeborg, Vandewalle Evelien, Zeyen Thierry

Trabeculectomy caused a small, statistically significant "with-the-rule" astigmatism shift, but glasses typically won't need changing.

Van Keer Karel, Breda João Barbosa, Pinto Luís Abegão, Stalmans Ingeborg, Vandewalle Evelien

Abegão Pinto Luís, Willekens Koen, Van Keer Karel, Shibesh Abraham, Molenberghs Geert, Vandewalle Evelien et al.

This large study found glaucoma patients have altered ocular blood flow (e.g., lower retrobulbar velocities) compared to controls, highlighting vascular dysfunction's potential role in clinical glaucoma management.

Van Keer Karel, Abegão Pinto Luís, Willekens Koen, Stalmans Ingeborg, Vandewalle Evelien

This study found a positive correlation between retinal oxygen saturation and choroidal thickness in healthy eyes, but not in glaucoma, suggesting impaired blood flow regulation in glaucoma patients.

Van Bergen Tine, Vandewalle Evelien, Moons Lieve, Stalmans Ingeborg

This study found combining adjunctive bevacizumab with reduced-dose, shorter-duration MMC improves glaucoma surgery outcomes, potentially reducing corneal toxicity.

Vandewalle Evelien, Abegão Pinto L, Olafsdottir Olof B, De Clerck Eline, Stalmans Peter, Van Calster Joachim et al.

This study found severe glaucoma correlates with increased retinal venule oxygen saturation and reduced arteriovenous difference, suggesting decreased oxygen consumption due to tissue loss, indicating metabolic changes in advanced disease.

Willekens Koen, Abegão Pinto Luís, Vandewalle Evelien, Marques-Neves Carlos, Stalmans Ingeborg

This study found that in normal-tension glaucoma patients, higher optic nerve sheath diameters were associated with lower ocular blood flow velocities, suggesting a potential link to disease pathology.

Vandewalle Evelien, Abegão Pinto Luís, Van Bergen Tine, Spielberg Leigh, Fieuws Steffen, Moons Lieve et al.

This study found intracameral bevacizumab with trabeculectomy significantly reduced the need for additional interventions (like needling) in glaucoma patients, improving absolute surgical success.

Vandewalle Evelien, Abegão Pinto Luis, Olafsdottir Olof Birna, Stalmans Ingeborg

Adding phenylephrine to tropicamide for glaucoma patients improved retinal image quality for oximetry, without altering retinal oxygen saturation or vessel diameter, making readings more reliable.

Abegão Pinto Luís, Vandewalle Evelien, De Clerck Eline, Marques-Neves Carlos, Stalmans Ingeborg

This study found spontaneous venous pulsation (SVP) is less common in glaucoma, and its absence in normal tension glaucoma (NTG) correlates with more severe damage and altered retinal blood flow, suggesting it's a potential NTG risk indicator.

Van Bergen Tine, Marshall Derek, Van de Veire Sara, Vandewalle Evelien, Moons Lieve, Herman Jean et al.

This study found LOXL2 is upregulated in glaucoma surgery scarring. Targeting LOXL2 with an antibody reduced fibrosis, inflammation, and angiogenesis, suggesting a promising new treatment for preventing surgical failure.

Abegão Pinto Luís, Vandewalle Evelien, Pronk Anna, Stalmans Ingeborg

This study found optic nerve sheath diameter correlated with IOP only in normal tension glaucoma patients, suggesting translaminar pressure gradient is crucial in NTG pathophysiology.

Abegão Pinto Luís, Vandewalle Evelien, Stalmans Ingeborg

Glaucoma patients show disturbed, nonlinear relationships between arterial resistance and pulsatility, unlike healthy individuals. This suggests impaired vascular autoregulation, potentially indicating a threshold for microvascular dysfunction.

Abegão Pinto Luís, Vandewalle Evelien, De Clerck Eline, Marques-Neves Carlos, Stalmans Ingeborg

Ophthalmic artery Doppler waveforms are altered in glaucoma, showing lower Sm/Dm ratios and ESA, correlating with visual field loss and nerve damage, suggesting vascular dysfunction contributes to disease progression.

Breusegem Christophe, Spielberg Leigh, Van Ginderdeuren Rita, Vandewalle Evelien, Renier Charlotte, Van de Veire Sara et al.

Preoperative topical steroids or NSAIDs improved trabeculectomy outcomes, significantly reducing the need for postoperative needling. Steroids also reduced the need for additional IOP-lowering medication.