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Olafsdottir Olof Birna

3 articles in GJC

3 articles in GJC

1.

Angiotensin Receptor Blockers in cyclodextrin nanoparticle eye drops: Ocular pharmacokinetics and pharmacologic effect on intraocular pressure.

Lorenzo-Soler Laura, Olafsdottir Olof Birna, Garhöfer Gerhard, Jansook Phatsawee, Kristinsdottir Iris Myrdal, Tan Aimin et al.

Acta OphthalmolNov 202014 citationsBasic Science

Topical ARB nanoparticle eye drops (candesartan, irbesartan) effectively delivered drug to rabbit eyes, with candesartan significantly lowering IOP. This suggests ARB eye drops could be a new glaucoma treatment.

2.

Phenylephrine 5% added to tropicamide 0.5% eye drops does not influence retinal oxygen saturation values or retinal vessel diameter in glaucoma patients.

Vandewalle Evelien, Abegão Pinto Luis, Olafsdottir Olof Birna, Stalmans Ingeborg

Acta OphthalmolDec 201328 citationsClinical Trial

Adding phenylephrine to tropicamide for glaucoma patients improved retinal image quality for oximetry, without altering retinal oxygen saturation or vessel diameter, making readings more reliable.

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