Angiotensin Receptor Blockers in cyclodextrin nanoparticle eye drops: Ocular pharmacokinetics and pharmacologic effect on intraocular pressure.
Lorenzo-Soler Laura, Olafsdottir Olof Birna, Garhöfer Gerhard, Jansook Phatsawee, Kristinsdottir Iris Myrdal, Tan Aimin et al.
Topical ARB nanoparticle eye drops (candesartan, irbesartan) effectively delivered drug to rabbit eyes, with candesartan significantly lowering IOP. This suggests ARB eye drops could be a new glaucoma treatment.