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Comparison of the in vitro tolerance and in vivo efficacy of traditional timolol maleate eye drops versus new formulations with bioadhesive polymers.
Andrés-Guerrero Vanessa, Vicario-de-la-Torre Marta, Molina-Martínez Irene T, Benítez-del-Castillo José Manuel, García-Feijoo Julián, Herrero-Vanrell Rocío
Invest Ophthalmol Vis SciJun 201127 citationsBasic Science
New unpreserved timolol formulations with bioadhesive polymers showed better cellular tolerance and similar IOP-lowering efficacy in rabbits compared to traditional drops. This suggests improved glaucoma treatment with less ocular toxicity.