Andrés-Guerrero Vanessa

🇤🇲 Universidad Complutense de Madrid

2 articles in GJC

Comparison of the in vitro tolerance and in vivo efficacy of traditional timolol maleate eye drops versus new formulations with bioadhesive polymers.

Andrés-Guerrero Vanessa, Vicario-de-la-Torre Marta, Molina-Martínez Irene T, Benítez-del-Castillo José Manuel, García-Feijoo Julián, Herrero-Vanrell Rocío

Invest Ophthalmol Vis SciJun 201127 citationsBasic Science

New unpreserved timolol formulations with bioadhesive polymers showed better cellular tolerance and similar IOP-lowering efficacy in rabbits compared to traditional drops. This suggests improved glaucoma treatment with less ocular toxicity.

Full abstract PubMed

The use of mucoadhesive polymers to enhance the hypotensive effect of a melatonin analogue, 5-MCA-NAT, in rabbit eyes.

Andrés-Guerrero Vanessa, Molina-Martínez Irene T, Peral Assumpta, de las Heras Beatriz, Pintor Jesús, Herrero-Vanrell Rocío

Invest Ophthalmol Vis SciMar 201114 citationsBasic Science

This study found bioadhesive polymers significantly enhanced the IOP-lowering effect and duration of a melatonin analogue (5-MCA-NAT) in rabbits, offering a promising, well-tolerated strategy for glaucoma treatment.

Full abstract PubMed

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Andrés-Guerrero Vanessa

Comparison of the in vitro tolerance and in vivo efficacy of traditional timolol maleate eye drops versus new formulations with bioadhesive polymers.

The use of mucoadhesive polymers to enhance the hypotensive effect of a melatonin analogue, 5-MCA-NAT, in rabbit eyes.