Pintor Jesús

Alkozi Hanan, Sánchez-Naves Juan, de Lara Maria Jesús Perez, Carracedo Gonzalo, Fonseca Begoña, Martinez-Aguila Alejandro et al.

This study found that elevated intraocular pressure (IOP) in humans and glaucoma mice correlates with significantly increased melatonin levels in the aqueous humor, suggesting a potential biomarker or role in glaucoma pathology.

Carracedo Gonzalo, Crooke Almudena, Guzman-Aranguez Ana, Pérez de Lara Maria J, Martin-Gil Alba, Pintor Jesús

Dinucleoside polyphosphates (NpnN) are crucial for ocular health, influencing tear film, drug delivery, and intraocular fluid dynamics. Their altered levels may indicate disease (e.g., dry eye, glaucoma) and offer therapeutic potential.

Andrés-Guerrero Vanessa, Molina-Martínez Irene T, Peral Assumpta, de las Heras Beatriz, Pintor Jesús, Herrero-Vanrell Rocío

This study found bioadhesive polymers significantly enhanced the IOP-lowering effect and duration of a melatonin analogue (5-MCA-NAT) in rabbits, offering a promising, well-tolerated strategy for glaucoma treatment.