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iPSC-Derived Trabecular Meshwork Cells Stimulate Endogenous TM Cell Division Through Gap Junction in a Mouse Model of Glaucoma.
Sui Shangru, Yu Hongxia, Wang Xiangji, Wang Wenyan, Yang Xuejiao, Pan Xiaojing et al.
Invest Ophthalmol Vis SciAug 202117 citationsBasic Science
iPSC-derived TM cells stimulate native TM cell division and restore function in glaucoma models via gap junctions, especially Cx43. This reveals a key mechanism to enhance regenerative glaucoma therapies.