Wheat Joe L

Wheat Joe L, Rangaswamy Nalini V, Harwerth Ronald S

This study found a structure-function model correlating OCT RNFL thickness and perimetry works for glaucoma, but needs adjustment for disease severity, improving clinical assessment across all stages.

Patel Nimesh B, Luo Xunda, Wheat Joe L, Harwerth Ronald S

This study found that retinal nerve fiber layer (RNFL) cross-sectional area, unlike thickness, remains constant regardless of scan distance from the optic nerve head. This suggests RNFL area may better reflect axonal content for glaucoma assessment.

Harwerth Ronald S, Wheat Joe L, Rangaswamy Nalini V

This study found age-related retinal nerve fiber layer thinning is partly due to decreasing axon density, not just cell loss, suggesting non-neuronal tissue increases with age.

Harwerth Ronald S, Wheat Joe L

This study modeled aging's impact on RGCs and RNFL. It found that age-related RNFL thinning is slower than RGC loss, suggesting a non-neural component partially compensates, crucial for interpreting OCTs.