Patel Nimesh B

Phu Jack, Wang Henrietta, Masselos Katherine, Tan Jeremy C K, Patel Nimesh B, Agar Ashish et al.

Frontloaded visual field testing (two per visit) detected over twice as many glaucoma progressors earlier than standard testing, enabling earlier intervention to preserve vision.

She Zhihui, Beach Krista M, Hung Li-Fang, Ostrin Lisa A, Smith Earl L, Patel Nimesh B

This study found that axial elongation in young monkeys correlates with changes in optic nerve head and macula GCIPL morphology, suggesting potential glaucoma risk factors in myopia.

Venkata Srinivasan Varsha, Carter-Dawson Louvenia, Patel Nimesh B

This study in primates linked visual field sensitivities (sizes I-V) to retinal ganglion cell counts. It found a structure-function model that estimates RGC content from standard perimetry, improving glaucoma monitoring.

Patel Nimesh B, Carter-Dawson Louvenia, Frishman Laura J

Transient IOP challenges revealed that baseline optic nerve features and axial elongation predict the extent of retinal ganglion cell loss in experimental glaucoma, suggesting potential for early risk assessment.

Pardon Laura P, Greenwald Scott H, Ferguson Connor R, Patel Nimesh B, Young Millennia, Laurie Steven S et al.

This study found astronauts with smaller preflight optic cup morphology are more prone to spaceflight-induced optic disc edema, suggesting targeted monitoring and countermeasures for those at higher risk.

Musial Gwen, Adhikari Suman, Mirhajianmoghadam Hanieh, Queener Hope M, Schill Alexander W, Patel Nimesh B et al.

This study found radial peripapillary capillary loss often precedes or coincides with nerve fiber layer thinning in experimental glaucoma, suggesting vascular factors may contribute to early axonal damage.

Pardon Laura P, Cheng Han, Chettry Pratik, Patel Nimesh B

Healthy individuals' neuroretinal rim thins daily, independent of IOP/ONSD. Head-down tilt prevents this thinning, suggesting translaminar pressure's role in optic nerve health and glaucoma pathogenesis.

Macias Brandon R, Patel Nimesh B, Gibson C Robert, Samuels Brian C, Laurie Steven S, Otto Christian et al.

This study found astronauts developed optic disc edema and choroidal thickening during spaceflight, and persistent axial length changes, highlighting ocular risks for long-duration missions.

Sullivan-Mee Michael, Patel Nimesh B, Pensyl Denise, Qualls Clifford

Glaucoma eyes with beta-zone atrophy showed significantly reduced juxtapapillary choroidal volume, suggesting this atrophy may indicate vascular compromise relevant to glaucoma progression.

Patel Nimesh B, Garcia Brenda, Harwerth Ronald S

Anterior segment power significantly affects SD-OCT RNFL thickness measurements due to magnification. Incorporating individualized ocular biometry can correct these errors, improving diagnostic accuracy.

Luo Xunda, Patel Nimesh B, Harwerth Ronald S, Frishman Laura J

Primate glaucoma caused a dramatic loss of low-frequency mfERG signals, which correlated with retinal nerve fiber layer thickness and visual field sensitivity. This offers an objective way to monitor early glaucoma.

Patel Nimesh B, Luo Xunda, Wheat Joe L, Harwerth Ronald S

This study found that retinal nerve fiber layer (RNFL) cross-sectional area, unlike thickness, remains constant regardless of scan distance from the optic nerve head. This suggests RNFL area may better reflect axonal content for glaucoma assessment.