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CYP3A4 Poor and Intermediate Metabolizers Have a Higher Rate of Steroid-Induced Intraocular Pressure Response.
Wright Jessica A, Xu Sarah C, Wong Mitchell H, El Melik Razan M, Hodge David, Sit Arthur J
J GlaucomaAug 20240 citationsObservational Study
This study found that individuals with reduced CYP3A4 steroid metabolizing phenotypes have a significantly higher rate of steroid-induced IOP elevation, which can help identify patients at risk.