Sit Arthur J

Kazemi Arash, Roy Chowdhury Uttio, Fautsch Michael P, Htoo Thurein M, Wirostko Barbara M, Hodge David O et al.

This study found episcleral venous pressure (EVP) and intraocular pressure (IOP) both peak in the morning and are correlated. Reducing EVP could be a key target for IOP regulation.

Kazemi Arash, Reitinger Jeremy C, Toris Carol B, Gulati Vikas, Fan Shan, Reed David M et al.

This study found that healthy individuals with higher baseline IOP, lower uveoscleral outflow, and higher BMI respond better to latanoprost, primarily due to increased uveoscleral outflow.

Sit Arthur J, Aihara Makoto, Khawaja Anthony P, Lin Shan C, Mansouri Kaweh, Miki Atsuya et al.

An expert group found lowering episcleral venous pressure (EVP), even modestly, may benefit glaucoma patients, especially those with low intraocular pressure or normal-tension glaucoma, offering individualized treatment.

Sit Arthur J, Toris Carol B, Gulati Vikas, Kazemi Arash, Gilbert Jesse, Fan Shan et al.

This study developed an objective method using root mean square error to grade tonography tracing quality, which strongly correlated with expert scores. This allows standardized, objective assessment of outflow facility measurements.

Gautam Natasha, Sit Arthur J

This case reports recurrent, delayed hyphema after OMNI MIGS, a novel complication emphasizing the need for long-term safety awareness in glaucoma patient management.

Wright Jessica A, Xu Sarah C, Wong Mitchell H, El Melik Razan M, Hodge David, Sit Arthur J

This study found that individuals with reduced CYP3A4 steroid metabolizing phenotypes have a significantly higher rate of steroid-induced IOP elevation, which can help identify patients at risk.

Kaplan Tyler M, Sit Arthur J, Patel Sanjay V, Roddy Gavin W

Four LASIK patients developed progressive paracentral visual field loss at low IOPs (≤12 mmHg), requiring single-digit targets. This suggests LASIK may increase glaucoma risk, possibly via reduced corneal hysteresis, necessitating lower IOP goals.

Liu Alice S, Lyons Lance J, Khanna Cheryl L, Roddy Gavin W, Hodge David O, Sit Arthur J

Increased laser energy caused more damage to single-use SLT lenses, which correlated with diminished treatment effectiveness. This suggests reconsidering their routine use.

WuDunn Darrell, Takusagawa Hana L, Rosdahl Jullia A, Sit Arthur J, Chopra Vikas, Ou Yvonne et al.

While 10-2 VF testing isn't routinely needed for early glaucoma, it can provide valuable information for patients with central 24-2 defects or macular OCT thinning, better correlating with structural changes.

Chopra Vikas, Takusagawa Hana L, Rosdahl Jullia A, Sit Arthur J, Richter Grace M, Ou Yvonne et al.

This review found aqueous shunts effectively lower IOP in adult open-angle glaucoma, especially non-valved devices. They are superior to trabeculectomy in previously operated eyes, but less successful as primary surgery.

Richter Grace M, Takusagawa Hana L, Sit Arthur J, Rosdahl Jullia A, Chopra Vikas, Ou Yvonne et al.

Combining trabecular MIGS with cataract surgery offers a small additional IOP reduction (1.6-2.3 mmHg) over cataract surgery alone for hypertensive OAG, with no clear benefit of one procedure over another.

Takusagawa Hana L, Hoguet Ambika, Sit Arthur J, Rosdahl Jullia A, Chopra Vikas, Ou Yvonne et al.

SLT is an effective, long-term treatment for open-angle glaucoma, comparable to ALT, and can be used as primary therapy, medication replacement, or adjunct.

Kaplan Tyler M, Sit Arthur J

A rare case showed a Hydrus Microstent caused UGH syndrome, highlighting this device as a potential cause of recurrent postoperative inflammation in glaucoma patients.

Kaplan Tyler M, Hammer Jon D, Kohli Darrel, Pacheco Johann M, Hodge David O, Khanna Cheryl L et al.

SLT efficacy was studied in immunosuppressed patients. Early IOP reduction was similar, but at one year, immunosuppressed patients had a diminished treatment response, suggesting less sustained benefit.

Sit Arthur J, Chen Teresa C, Takusagawa Hana L, Rosdahl Jullia A, Hoguet Ambika, Chopra Vikas et al.

Corneal hysteresis is lower in glaucoma patients and linked to increased progression risk, complementing current assessments for disease risk, even in normal-tension or controlled IOP cases.

Shah Saumya M, Boopathiraj Nithya, Starr Matthew R, Dalvin Lauren A, AbouChehade Jackson, Damento Gena et al.

This study found anti-VEGF injections for AMD didn't increase glaucoma risk. However, treated eyes with glaucoma needed more medications and showed faster visual field loss than some controls, requiring careful monitoring.

Roddy Gavin W, Sit Arthur J

Advancing Tenon's layer during trabeculectomy improved bleb morphology, creating diffuse, low-lying, non-ischemic blebs. This modification may enhance surgical success and reduce complications.

Kazemi Arash, McLaren Jay W, Sit Arthur J

Topical phenylephrine's effect on episcleral venous pressure (EVP) and intraocular pressure (IOP) was studied. While IOP increased, EVP decreased, indicating IOP elevation isn't due to increased EVP, a clinically relevant finding for glaucoma management.

Kazemi Arash, Zhou Boran, Zhang Xiaoming, Sit Arthur J

Glaucoma patients showed lower ocular rigidity than healthy eyes, despite similar corneal elasticity. This suggests scleral biomechanics, not corneal, are key in glaucoma pathogenesis.

Kilgore Khin P, Wang Feng, Stern Nicole C, Sabbagh Nouran, Jamali Sepideh, White Launia J et al.

This study found Ahmed FP7 and Baerveldt 350 glaucoma drainage devices significantly increase diplopia risk (~20%) compared to Baerveldt 250 or controls (~5%). This risk should be discussed preoperatively.

Belamkar Aditya V, Mansukhani Sasha A, Savica Rodolfo, Spiegel Matthew R, Hodge David O, Sit Arthur J

This study found open-angle glaucoma patients had a decreased rate of developing dementia compared to the general population, suggesting a potential inverse relationship or different neurodegenerative pathways.

WuDunn Darrell, Takusagawa Hana L, Sit Arthur J, Rosdahl Jullia A, Radhakrishnan Sunita, Hoguet Ambika et al.

OCTA detects decreased peripapillary, macular, and choroidal vessel density in glaucoma, correlating with severity and progression, thus complementing existing diagnostic tools.

Sit Arthur J, Gupta Divakar, Kazemi Arash, McKee Hayley, Challa Pratap, Liu Katy C et al.

Netarsudil significantly improves trabecular outflow facility and lowers IOP in glaucoma/OHT patients, acting on the conventional outflow pathway. This confirms its mechanism for effective pressure reduction.

Mansukhani Sasha A, Barkmeier Andrew J, Bakri Sophie J, Iezzi Raymond, Pulido Jose S, Khanna Cheryl L et al.

Mansukhani Sasha A, Barkmeier Andrew J, Bakri Sophie J, Iezzi Raymond, Pulido Jose S, Khanna Cheryl L et al.

This study found vitrectomy significantly increases the 10-year risk of primary open-angle glaucoma (POAG). Clinically, this highlights the need for long-term POAG screening after vitrectomy.