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Large-Scaled Proteomics Analysis for Glaucoma: Integrated Genetics, Multi-Omics, UK Biobank and Therapeutic Analysis.
Xu Jianming, Gao Yuelan, Yu Jun, Xu Zihe, Zhang Yuzhou, Pang Chi Pui et al.
Invest Ophthalmol Vis SciFeb 20260 citationsCohort Study
Multi-omics identified 26 plasma proteins, including novel COL24A1 and EFEMP1, causally linked to glaucoma. EFEMP1 strongly predicts incident glaucoma, offering promising biomarkers and therapeutic targets.