Akagi Tadamichi

Peripapillary and Macular Vessel Density in Patients with Glaucoma and Single-Hemifield Visual Field Defect.

Reduced peripapillary and macular vessel density was detectable in the perimetrically intact hemiretinae of glaucoma eyes with a single-hemifield defect.

Progressive Macula Vessel Density Loss in Primary Open-Angle Glaucoma: A Longitudinal Study.

With a mean follow-up of less than 14 months, eyes with POAG had significantly faster loss of macula vessel density than either glaucoma-suspect or healthy eyes.

Reproducibility of Optical Coherence Tomography Angiography Macular and Optic Nerve Head Vascular Density in Glaucoma and Healthy Eyes.

Reproducibility of OCT-A ONH and macula vessel density measurements is good. Moreover, glaucoma patients have sparser vessel density with poorer reproducibility than healthy subjects.

Optical Coherence Tomography Angiography Macular Vascular Density Measurements and the Central 10-2 Visual Field in Glaucoma.

Loss of OCT-A macula vessel density is associated with central 10-2 VF defects. Macula vessel density is a clinically relevant parameter that may enhance monitoring of glaucoma suspects and patients.

Macula Vessel Density and Thickness in Early Primary Open-Angle Glaucoma.

Both GCC thinning and macula vessel density dropout were detectable in preperimetric and early POAG eyes.

The Association Between Macula and ONH Optical Coherence Tomography Angiography (OCT-A) Vessel Densities in Glaucoma, Glaucoma Suspect, and Healthy Eyes.

The strength of the association of VD with cpRNFL and mGCC thicknesses varies by retinal layer.

Rates of Local Retinal Nerve Fiber Layer Thinning before and after Disc Hemorrhage in Glaucoma.

Although the rate of RNFL thinning worsened in a DH quadrant after DH, glaucoma treatment intensification may have a beneficial effect in reducing this rate of thinning.

Progression of Primary Open-Angle Glaucoma in Diabetic and Nondiabetic Patients.

POAG patients with treated type 2 DM, who had no detectable diabetic retinopathy, had significantly slower rates of RNFL thinning compared to those without diagnosed DM.

Deep-Layer Microvasculature Dropout by Optical Coherence Tomography Angiography and Microstructure of Parapapillary Atrophy.

Parapapillary deep-layer microvasculature dropout was associated with the presence and larger width of γPPA, but not with the βPPA+BM width.

Anterior Segment Optical Coherence Tomography Angiography Imaging of Conjunctiva and Intrasclera in Treated Primary Open-Angle Glaucoma.

AS-OCTA images may be useful for the objective assessment of conjunctival hyperemia and helpful for understanding the pathophysiology of post-trabecular aqueous humor outflow.

Association of Glaucoma-Susceptible Genes to Regional Circumpapillary Retinal Nerve Fiber Layer Thickness and Visual Field Defects.

Genetic association analyses using the cpRNFLT with 768 points suggest that the CDKN2B gene was associated with paracentral/lower hemifield scotomas.

Visualization of the Lamina Cribrosa Microvasculature in Normal and Glaucomatous Eyes: A Swept-source Optical Coherence Tomography Angiography Study.

This is the first demonstration of imaging of the inner LC microvasculature, which, in agreement with previous histologic reports, was arranged in a polygonal pattern.

Association of Bruch's membrane opening and optic disc morphology to axial length and visual field defects in eyes with primary open-angle glaucoma.

The optic disc ovality was associated with both the axial length and MD, whereas BMO ovality was not. Attention should be paid to the influence of the axial length-related enlargement of the BMO.

Association between Rates of Retinal Nerve Fiber Layer Thinning and Previous Disc Hemorrhage in Glaucoma.

A history of DH is an independent risk factor for faster rates of RNFL thinning in non-DH quadrants and in DH quadrants; this risk is present even in eyes that exhibited DH several years earlier.

Relationship between Intraocular Pressure and Coffee Consumption in a Japanese Population without Glaucoma: The Nagahama Study.

Frequent coffee consumption was associated with a slightly lower IOP in people without glaucoma but was not associated with a decreased risk of glaucoma developing.

Anterior Segment OCT Angiography Images of Avascular Bleb after Trabeculectomy.

Association between Rates of Retinal Nerve Fiber Layer Thinning after Intraocular Pressure-Lowering Procedures and Disc Hemorrhage.

POAG or glaucoma suspect eyes with a history of DH should be carefully followed after IOP-lowering procedures.

Exploration of the cutoff values of axial length that is susceptible to develop advanced primary open angle glaucoma in patients aged less than 50 years.

Axial length measurement was clinically significant in assessing risk of severe or central visual field defects in young patients with POAG.

Risk of Glaucoma and Undergoing Glaucoma Surgery in Myopic and Highly Myopic Eyes: A Nationwide Population-Based Cohort Study.

Both myopia and high myopia significantly increase the risk of glaucoma developing and the likelihood of requiring glaucoma surgery, especially for invasive filtering surgeries.

Associations between Clustered Visual Field Progression and Locations of Disc Hemorrhages in Glaucoma: A 3-Year Prospective Study.

The location of DH was strongly associated with corresponding clustered VF progression in patients with POAG.

Comparison of a Novel Head-Mounted Objective Auto-perimetry (Gaze Analyzing Perimeter) and Humphrey Field Analyzer.

The results indicate that the GAP provides VF assessment outcomes comparable to those of the HFA.

Structure function relationship of paracentral visual field impairment in myopic patients with primary open-angle glaucoma.

Comparison of Surgical Outcomes of Ab Interno Trabeculotomy Using Tanito Microhook, Suture, and Trabectome.

TMH, sLOT, and TOM provide similar IOP-lowering efficacy. Considering patient factors-such as baseline IOP and lens status-and using available devices while avoiding excessively wide incisions may contribute to favorable surgical outcomes.

Outcomes of Ahmed and Baerveldt Glaucoma Drainage Devices in Japanese Patients.

In this large-scale real-world study, no significant differences in surgical outcomes were observed between the Ahmed glaucoma valve and the Baerveldt glaucoma implant.

Cone Integrity in Glaucoma: An Adaptive-Optics Scanning Laser Ophthalmoscopy Study.

Both AO-SLO and SDOCT showed cone integrity in eyes with glaucoma, even in areas with visual field and nerve fiber loss.

Microvascular Density in Glaucomatous Eyes With Hemifield Visual Field Defects: An Optical Coherence Tomography Angiography Study.

Microvascular reduction was associated with VF defects in a region-specific manner: significantly and partially in the peripapillary retina and optic disc, respectively.

Clustering of Combined 24-2 and 10-2 Visual Field Grids and Their Relationship With Circumpapillary Retinal Nerve Fiber Layer Thickness.

Explanatory factor analysis revealed detailed patterns of glaucomatous VF defects and glaucomatous cpRNFL thinning.

Effect of Axial Length on Macular Ganglion Cell Complex Thickness and on Early Glaucoma Diagnosis by Spectral-Domain Optical Coherence Tomography.

The inferior mGCC was thinner in eyes with longer AL.

Transient Ciliochoroidal Detachment After Ab Interno Trabeculotomy for Open-Angle Glaucoma: A Prospective Anterior-Segment Optical Coherence Tomography Study.

Ciliochoroidal detachment after ab interno trabeculotomy was not rare and was associated with low IOP immediately after surgery.

Microstructure of Peripapillary Atrophy and Subsequent Visual Field Progression in Treated Primary Open-Angle Glaucoma.

There were significant differences in VF progression according to the microstructure of the β-zone PPA in eyes with POAG.

Glaucoma Tube Changes After Suture Lysis Assessed by High-Resolution Anterior Segment Optical Coherence Tomography.

Structural dissociation of optic disc margin components with optic disc tilting: a spectral domain optical coherence tomography study.

Locations of the SO at not only the temporal, but also the nasal side of the optic disc are nasally shifted from the BMO with optic disc tilting and axial length elongation in glaucomatous eyes, and are significantly correlated to each other.

Comparison of Longitudinal Changes in Functional and Structural Measures for Evaluating Progression of Glaucomatous Optic Neuropathy.

Functional (SAP) and structural (SD-OCT) testing can detect longitudinal changes of glaucomatous optic neuropathy, but in different ways.

Sensitivity and specificity for detecting early glaucoma in eyes with high myopia from normative database of macular ganglion cell complex thickness obtained from normal non-myopic or highly myopic Asian eyes.

The significantly higher specificity of the myopic normative database for detecting early glaucoma in highly myopic eyes will lead to fewer false positive diagnoses.