Fan Shan

Mechanism of Action of Selective Laser Trabeculoplasty and Predictors of Response.

The IOP-lowering effect of SLT is mediated through an increase in outflow facility. There is no contralateral effect. Higher aqueous flow and lower outflow facility may be predictive of better response to SLT.

Eye Dynamics and Engineering Network Consortium: Baseline Characteristics of a Randomized Trial in Healthy Adults.

The current study from the EDEN Consortium describes measurement methods and data analyses with emphasis on IOP variability.

IOP Reduction in Nonhuman Primates by Microneedle Injection of Drug-Free Hydrogel to Expand the Suprachoroidal Space.

IOP was reduced in nonhuman primates for over one month by sustained SCS expansion.

Assessing Agreement of Intraocular Pressure from Four Mechanistically Different Tonometers in the Eye Dynamics and Engineering Network Clinical Trial.

When adjusted for proparacaine's effect on IOP, 3 tonometers were equivalent between each other when determined by equivalence statistical testing with equivalence bounds ± 2 mmHg.

Objective Grading of Tonography Tracings for the Measurement of Outflow Facility.

Objective assessment of pneumatonography tracings can be performed using RMSE of a fitted line and calculation of a predicted quality score that closely matches scores given by expert graders.