Malik Y. Kahook

Outcomes of Kahook Dual Blade Goniotomy with and without Phacoemulsification Cataract Extraction.

Goniotomy with the KDB has a favorable safety profile and is an effective procedure at reducing IOP and medication burden as a standalone procedure or combined with phacoemulsification.

Long-term Safety and Ocular Hypotensive Efficacy Evaluation of Netarsudil Ophthalmic Solution: Rho Kinase Elevated IOP Treatment Trial (ROCKET-2).

In this randomized, double-masked trial, once-daily dosing of netarsudil 0.02% was effective, consistently lowering IOP through 12 months, and was tolerated by the majority of patients.

Intraocular Pressure Elevation Following Intravitreal Anti-VEGF Injections: Short- and Long-term Considerations.

Furthermore, there are challenges in determining the impact of postinjection IOP elevation on the health of the retinal ganglion cells, particularly given the often-existing comorbidities of retinal and glaucoma pathology.

Refractive outcomes of phacoemulsification cataract surgery in glaucoma patients.

Patients with a diagnosis of glaucoma were more likely to have a refractive surprise and/or worse visual outcome after phacoemulsification cataract surgery.

The Effects of Glaucoma and Glaucoma Therapies on Corneal Endothelial Cell Density.

This review will summarize the reported effects of glaucoma and its treatment on ECL.

Efficacy of Goniotomy With Kahook Dual Blade in Patients With Uveitis-associated Ocular Hypertension.

On the basis of this small case series, KDB goniotomy may be a safe, less invasive, and effective first-line surgical alternative for patients with uveitis-associated OHTN or glaucoma refractory to medical therapy.

Predicting Glaucoma Before Onset Using a Large Language Model Chatbot.

The performance of ChatGPT4.0 in forecasting development of glaucoma 1 year before onset was reasonable.

Histopathologic Examination of Trabecular Meshwork Changes After Trabecular Bypass Stent Implantation.

These findings indicate that inflammatory and fibrotic changes are present surrounding the device with clear differences noted when compared with both healthy and glaucomatous controls.

Postoperative Inflammation After Endoscopic Cyclophotocoagulation: Racial Distribution and Effect on Outcomes.

PAU is common after combined phacoemulsification and ECP and is significantly correlated with race. Although PAU may require prolonged postoperative treatment, our data does not support poorer VA or IOP outcomes.

Clinical Outcomes of Ahmed ClearPath Implantation in Glaucomatous Eyes: A Novel Valveless Glaucoma Drainage Device.

The new ACP appears to be safe and efficacious as a standalone procedure or in combination with other procedures for uncontrolled glaucoma, and may be considered as a GDD option for patients in whom its…

24-Hour Intraocular Pressure Control with Fixed-dose Combination Brinzolamide 1%/Brimonidine 0.2%: A Multicenter, Randomized Trial.

This large, multicenter study of 24-hour IOP control with BBFC met its primary end point; BBFC demonstrated significantly superior 24-hour IOP-lowering efficacy versus vehicle after 4 weeks of 3-times-daily treatment in subjects with OAG or…

Patient Acceptance of Sustained Glaucoma Treatment Strategies.

Most glaucoma patients considered sustained drug-delivery modalities acceptable alternatives to IOP-lowering eye drops, but only when they were said to obviate surgery or demonstrate greater efficacy than eye drops.

The Utility of iCare HOME Tonometry for Detection of Therapy-Related Intraocular Pressure Changes in Glaucoma and Ocular Hypertension.

Home tonometry with iCare HOME reliably detects therapy-related IOP changes in patients with glaucoma and ocular hypertension.

Outcomes of Kahook Dual Blade Goniotomy for Uveitis Associated Open Angle Glaucoma or Ocular Hypertension.

This larger case series shows that some patients with uveitis-associated ocular hypertension or glaucoma with an open angle may have success with KDB goniotomy.

Subjective and Objective Measurement of Sleep Quality and Activity in Glaucoma.

In this study, patients with glaucoma demonstrated several subjective and objective differences in sleep function when compared with controls, whereas physical activity metrics were similar.

The Role of Artificial Intelligence in the Diagnosis and Management of Glaucoma.

Applications derived from this field of computer science can improve the quality and robustness of insights obtained from clinical data that can enhance the clinician's approach to patient care.

Tenon Cyst Patch Graft for Ahmed Glaucoma Valve Tube Exposure: Case Series Report.

The use of a Tenon cyst autograft for the surgical repair of a tube exposure is valuable, as it involves using autologous scar tissue that is available in eyes that have undergone AGV implantation.

Perceptions of Marijuana Use for Glaucoma from Patients, Cannabis Retailers, and Glaucoma Specialists.

Few glaucoma specialists have recommended marijuana as a treatment for glaucoma, and an even smaller percentage of patients report its use as a treatment for their glaucoma.

A Comparison of Clinical Outcomes After XEN Gel Stent and EX-PRESS Glaucoma Drainage Device Implantation.

In this population, although the XEN stent offers a better safety profile and fewer postoperative clinic visits, complete surgical success was inferior to the EX-PRESS shunt.

Tolerability and Functionality of a Wireless 24-Hour Ocular Telemetry Sensor in African American Glaucoma Patients.

The wireless ocular sensor is well tolerated over a 24-hour period in African American patients with POAG despite transient changes in visual acuity and conjunctival erythema.

Optimum time for angle visualization during ab interno glaucoma surgery: Before or after phacoemulsification.

In combination phacoemulsification and angle-based glaucoma procedures, there appears to be no significant angle visualization difference whether the surgeon chooses to complete angle surgery before or after phacoemulsification; therefore, the decision of surgical order should…

A Survey of Patient Perceptions and Preferences for Glaucoma Treatment with Intravitreal Injections.

Patients are open to alternative methods of drug delivery, and their willingness to undergo more invasive treatments, like IVI, for glaucoma rises with a longer theoretical duration between treatments.

Relationship Between Contact Lens Sensor Output Parameters and Visual Field Progression in Open-angle Glaucoma: Assessment of a Practical Tool to Guide Clinical Risk-assessment.

PR provided comparable predictions of the risk of fast VF progression as did physician estimates based on all available clinical data.

Optic Cup and Disc Segmentation of Fundus Images Using Artificial Intelligence Externally Validated With Optical Coherence Tomography Measurements.

The proposed AI pipeline had strong correlation with OCT measurements and performed comparably to EHR assessments, with high repeatability. Increased diversity and cardinality of training data improved performance and generalizability to unseen datasets.

The Effect of Endoscopic Cyclophotocoagulation on the Outcomes of Excisional Goniotomy With and Without Phacoemulsification.

Both standalone KDB goniotomy with ECP and the PEcK procedure are efficacious at lowering IOP and glaucoma medication burden.

Consultation Section: Glaucoma. July consultation #7.

Reply to Comment on: Predicting Glaucoma Before Onset Using a Large Language Model Chatbot.

Outcomes after combined phacoemulsification and trabecular microbypass stent implantation in controlled open-angle glaucoma.

Combined cataract surgery and trabecular microbypass stent implantation was statistically effective in reducing IOP and/or medication burden in OAG patients with a low preoperative IOP.

Glaucoma Patient Treatment Preferences.

Endophthalmitis With Corneal Infiltrate After EX-PRESS Glaucoma Drainage Device Implantation.

Endophthalmitis after EX-PRESS implantation may be complicated by corneal infiltrate formation and persistent infection.

Ability of Bottle Cap Color to Facilitate Accurate Patient-Physician Communication Regarding Medication Identity in Patients with Glaucoma.

Physician understanding of patient medication use based solely on bottle cap color is frequently incorrect, particularly in patients with glaucoma who may have color vision deficiency.

The Utility of Cap Color and Bottle Characteristics for Topical Glaucoma Therapy.

Aflibercept for the treatment of neovascular glaucoma.

These results suggest that intravitreal aflibercept may be an effective treatment for stage 1 and 2 NVG, resulting in rapid and sustained regression of NVI and NVA as well as control of IOP.

Psychometric properties of the Glaucoma Treatment Compliance Assessment Tool in a multicenter trial.

The newest version of the Glaucoma Treatment Compliance Assessment Tool showed acceptable psychometric properties.

December consultation #7.