Kashiwagi Kenji

Change in visual acuity and associated risk factors after trabeculectomy with adjunctive mitomycin C.

Visual acuity was significantly reduced after MMC trabeculectomy in 5 years, and we identified several risk factors associated with this complication.

Investigating the usefulness of a cluster-based trend analysis to detect visual field progression in patients with open-angle glaucoma.

Cluster-based trend analysis and mTD trend analysis results were significantly associated in all clusters and with all lengths of VF series.

Validating Variational Bayes Linear Regression Method With Multi-Central Datasets.

VBLR outperformed OLSLR to predict future VF progression, and the VBLR has a potential to be a helpful tool at clinical settings.

Genetic Variants Associated With the Onset and Progression of Primary Open-Angle Glaucoma.

The results indicate that non-IOP-related (optic nerve vulnerability) rather than IOP-related (IOP elevation) genetic variants may play an important role in the onset of POAG (family history of glaucoma) and that IOP-related rather than non-IOP-related…

Effects of ocular and systemic factors on the progression of glaucomatous visual field damage in various sectors.

Smoking status is related to glaucomatous VF progression in all sectors of the inferior hemifield.

Genetic Variant Near PLXDC2 Influences the Risk of Primary Open-angle Glaucoma by Increasing Intraocular Pressure in the Japanese Population.

The genetic variant near the PLXDC2 gene was found to influence the risk of POAG by increasing IOP in the Japanese population.

Risk of Glaucoma and Undergoing Glaucoma Surgery in Myopic and Highly Myopic Eyes: A Nationwide Population-Based Cohort Study.

Both myopia and high myopia significantly increase the risk of glaucoma developing and the likelihood of requiring glaucoma surgery, especially for invasive filtering surgeries.

Genetic Variants Associated With a History of Glaucoma Surgery in Japanese Patients With Primary Open Angle Glaucoma.

IOP-related, but not optic nerve-related, genetic variants were associated with a history of glaucoma surgery in Japanese patients with POAG.

Deep learning model for extensive smartphone-based diagnosis and triage of cataracts and multiple corneal diseases.

The AI system achieved promising performance in the diagnosis of cataracts and corneal diseases.

Evaluation of Glaucoma Progression in Large-Scale Clinical Data: The Japanese Archive of Multicentral Databases in Glaucoma (JAMDIG).

Age and the degree of VF damage were related to future progression.

Involvement of genetic variants associated with primary open-angle glaucoma in pathogenic mechanisms and family history of glaucoma.

Non-IOP-related genetic variants contribute to the pathogenesis of HTG as well as NTG. A positive family history of glaucoma in cases of POAG is thought to reflect the influence of genetic variants predisposing to POAG.