Br J Ophthalmol
Br J OphthalmolAugust 2017Research Support, Non-U.S. Gov't

Effects of ocular and systemic factors on the progression of glaucomatous visual field damage in various sectors.

IOP & Medical TherapyVisual Field

Summary

Smoking status is related to glaucomatous VF progression in all sectors of the inferior hemifield.

Abstract

BACKGROUND/AIM

To investigate the effects of ocular and systemic risk factors for glaucomatous progression in different sectors of the visual field (VF).

METHOD

409 eyes from 268 patients with 10 reliable VFs from the Japanese Archive of Multicentral Databases in Glaucoma (JAMDIG) were investigated. VFs were divided into six sectors (mean total deviation (mTD), mTDand mTD, >20°, 10-20° and 20°, 10-20° and <10° in the inferior hemifield, respectively). The relationship between sectorial progression rate and eight variables (age, mTD at baseline VF, average intraocular pressure (IOP), SD of IOP, systemic hypertension, migraine, family history of glaucoma and smoking status) was investigated.

RESULT

The mTD progression rate was -0.21 dB/year. Older age was related to progression of mTD, mTD, mTDand mTD. Mean IOP was not related to progression in any VF sector; however, a larger SD of IOP was related to progression of mTD, mTD, mTDand mTD. Smoking status was related to progression in all inferior VF sectors (mTD, mTDand mTD).

CONCLUSIONS

Smoking status is related to glaucomatous VF progression in all sectors of the inferior hemifield.

Keywords

Glaucoma

Discussion

Comments and discussion will appear here in a future update.