Liang Yuanbo

Effect of Community Screening on the Demographic Makeup and Clinical Severity of Glaucoma Patients Receiving Care in Urban China.

Glaucoma patients detected through community screening had significantly milder damage, and were more likely to include underserved groups (women, elderly) than those newly diagnosed in a clinic in this setting.

Parapapillary Choroidal Microvasculature Dropout Is Associated With the Decrease in Retinal Nerve Fiber Layer Thickness: A Prospective Study.

There is a significant correlation between the presence of MvD and decrease in RNFL thickness in NTG patients.

Efficacy of bleb-independent penetrating canaloplasty in primary angle-closure glaucoma: one-year results.

Penetrating canaloplasty in PACG appeared to have good efficacy and safety profiles in this pilot study. Further studies are justified.

Integrating opportunistic glaucoma screening into general health examinations in China: A pilot study.

This novel screening model provides opportunities to improve glaucoma detection at low cost. Interventions to improve follow-up are needed.

Achieving Inner Aqueous Drain in Glaucoma Secondary to Iridocorneal Endothelial Syndrome: One Year Results of Penetrating Canaloplasty.

Penetrating canaloplasty rescued the inner aqueous outflow in ICE eyes and demonstrated acceptable success in IOP control with few complications, providing a new option for the management of GS-ICE.

Efficacy of Combined Phacoemulsification and Goniosynechialysis in Primary Angle Closure Disease With Different Degrees of Peripheral Anterior Synechiae.

Phaco-GSL for the treatment of PACD showed equally effective IOP control regardless of the extent of preoperative PAS.

Natural History and Risk Factors for Glaucoma Progression in Chinese Patients With Normal-Tension Glaucoma.

Nearly two-thirds of untreated Chinese patients with NTG progressed over an average follow-up of 70 months by VF, RNFL, or GCIPL.

Effects of Exercise on Optic Nerve and Macular Perfusion in Glaucoma and Normal Subjects.

Moderate physical exercise for 20 minutes increased blood flow in the macula region without significant change to the optic nerve and lowered intraocular pressure in glaucoma and normal subjects.

Progression of Macular Vessel Density in Primary Open-Angle Glaucoma: A Longitudinal Study.

The mGCIPL thickness, pRNFL thickness, and mVD decreased over time in POAG eyes. The rate of reduction of mVD was significantly influenced by the baseline measurements of mGCIPL thickness, pRNFL thickness, and mVD.

Outcomes of Penetrating Canaloplasty in Childhood Glaucoma.

Penetrating canaloplasty demonstrated good safety and efficacy in eyes with childhood glaucoma, and may be considered an option for managing refractory childhood glaucoma.

Efficacy and safety of penetrating canaloplasty versus ab externo canaloplasty for primary open-angle glaucoma: A randomized controlled trial.

Compared to ab externo canaloplasty, penetrating canaloplasty had a greater surgical success rate and better IOP reduction with a comparable rate of complications.

Prevalence and Ocular Biometric Characteristics of Myopia in Primary Angle Closure Disease in Rural China: The Handan Eye Study.

Myopia was common among persons with PACD who were less than 40 years of age in this rural Chinese population, and over half of those with PACG were myopic.

Assessment of Causality Between Diet-Derived Antioxidants and Primary Open-Angle Glaucoma: A Mendelian Randomization Study.

Our study did not support a causal association among six diet-derived circulating antioxidants, POAG, and glaucoma-related traits.

Progressive peripapillary capillary vessel density loss and long-term visual field progression in Normal tension glaucoma.

In individuals with NTG, faster VF progression was linked to a quicker reduction in pcVD, suggesting a positive correlation between pcVD decline and VF deterioration.

Low Intraocular Pressure Induces Fibrotic Changes in the Trabecular Meshwork and Schlemm's Canal of Sprague Dawley Rats.

In conclusion, a persistence of L-IOP for 2 weeks may contribute to fibrosis in the TM and SC and might be detrimental to conventional AHO in SD rat eyes.

Different retinal microvascular response to flicker light between normal-tension glaucoma and high-tension primary open-angle glaucoma detected with optical coherence tomography angiography.

Visual task-evoked vasoreactivity changes provide additional information in the understanding and assessment of the pathophysiological mechanisms of glaucoma.

A Novel Rabbit Model of Angle-Closure Glaucoma Via Ciliary Block and Elevated Trans-Lens Pressure Difference.

We successfully developed a reproducible rabbit model in which ciliary block-induced trans-lens pressure difference acts as a pivotal mechanistic link to anterior chamber shallowing, angle closure, and sustained IOP elevation, recapitulating key features of human…

Ocular and Systemic Risk Factors and Biomarkers for Primary Glaucoma: An Umbrella Review of Systematic Reviews With Meta-Analyses.

This umbrella review highlights the evidence hierarchy of various ocular and systemic risk factors and biomarkers associated with glaucoma. Further high-quality studies are essential to strengthen the evidence base.

Assessing Vascular and Structural Hemiretinal Asymmetry at Different Stages of Normal Tension Glaucoma Using Optical Coherence Tomography.

The hemiretinal asymmetry parameter exhibits a clear trend across different stages of NTG, aiding in the staging of NTG before reaching the moderate stage.

Comparative Analysis of Melbourne Rapid Fields Web-Browser Perimeter and Humphrey Field Analyzer in Chinese Glaucoma Patients.

MRF offers a reliable, efficient, and patient-friendly alternative to traditional VF testing for Chinese patients.

Walking More Than 10,000 Steps Per Day May Be Associated With Increased Optic Disc Vessel Density in Patients With Primary Open Angle Glaucoma.

Patients with POAG with ADS >10,000 exhibited higher papillary VD compared with those with ADS ≤10,000, implying that increasing daily steps, particularly exceeding 10,000 steps, may potentially enhance ocular blood flow.

Progressive Macular Vessel Density Loss Observed on Optical Coherence Tomography Angiography in Glaucoma Patients With Single-Hemifield Visual Field Defects.

Faster hemispheric mVD loss was found in the affected hemifield of POAG patients without significant changes in hemispheric thickness. The progression of mVD loss was associated with the severity of VF damage.

Performance of a Glaucoma Screening Program Compared With Opportunistic Detection in China.

The glaucoma screening program was effective at detecting early disease, especially normal tension glaucoma and supplemented opportunistic detection of glaucoma.

The aqueous humour dynamics in primary angle closure disease: a computational study.

The association among the ACR, MFV and pressure is an ascending curve in PACD, and ACR of 180° and 270° are two critical turning points.

Utility Analysis of Vision-related Quality of Life in Patients With Glaucoma and Different Perceptions from Ophthalmologists.

Utility values are considerably decreased in Chinese patients with glaucoma.