Lum Flora

Smoking Is Associated with Higher Intraocular Pressure Regardless of Glaucoma: A Retrospective Study of 12.5 Million Patients Using the Intelligent Research in Sight (IRIS®) Registry.

Current smokers and past smokers have higher IOP than patients who never smoked. This difference is higher in patients with an underlying glaucoma diagnosis.

Special Commentary: Reporting Clinical Endpoints in Studies of Minimally Invasive Glaucoma Surgery.

The suggested MCID for the cumulative probability of success for MIGS combined with CE-IOL at 2 years is 65%.

Demographic and Clinical Characteristics Associated with Minimally Invasive Glaucoma Surgery Use: An Intelligent Research in Sight (IRIS®) Registry Retrospective Cohort Analysis.

This analysis highlights the importance of capturing race-ethnicity data and other pertinent patient characteristics in electronic health records to provide insight into practice patterns.

Intraocular Pressure Changes Following Stand-Alone Phacoemulsification: An IRISRegistry Analysis.

Eyes both with and without glaucoma that underwent stand-alone phacoemulsification had a significant decrease in IOP through the 90-day postoperative period compared to baseline and phakic fellow eyes.

What Do We Really Know about the Effectiveness of Glaucoma Interventions?: An Overview of Systematic Reviews.

Most systematic reviews evaluating interventions for glaucoma are of poor reliability.

Intraocular Pressure Spike Following Stand-Alone Phacoemulsification in the IRIS® Registry (Intelligent Research in Sight).

Higher baseline IOP, male sex, glaucoma, Black race, older age, and complex cataract coding were associated with early postoperative IOP spike, whereas diabetes and postoperative aphakia were protective against a spike after stand-alone phacoemulsification.

Risk Factors for Repeat Keratoplasty After Endothelial Keratoplasty-An IRIS Registry Analysis.

Black race, government-based insurance plans, and smoking were identified as independent factors associated with repeat keratoplasty in addition to history of glaucoma, glaucoma surgery, and prior graft failure or bullous keratopathy as surgical indication.

Risk of Glaucoma Surgery After Corneal Transplant Surgery in Medicare Patients.

Despite literature suggesting that more angle-altering cornea surgeries confer higher risk, we found no statistically significant differences among various transplant groups.

Prevalence and Risk Factors of Blindness Among Primary Angle Closure Glaucoma Patients in the United States: An IRIS Registry Analysis.

Blindness affects 1 of 9 patients with newly diagnosed PACG in the IRIS Registry.

Tube Versus Trabeculectomy IRISRegistry 1-Year Composite Outcome Analysis with Comparisons to the Randomized Controlled Trial.

Our results were different from those in the TVT RCT. Possible reasons include non-Baerveldt tubes, greater severity among tube eyes, and practice patterns that reflect real-world data, which are different than those in RCTs.

The Tube Versus Trabeculectomy IRIS® Registry Study: Cohort Selection and Follow-up and Comparisons to the Randomized Controlled Trial.

The TVT IRIS Registry cohort had several significant treatment group differences at baseline, whereas there had been none in the TVT RCT cohort.

An IRIS Registry-Based Assessment of Primary Open-Angle Glaucoma Practice Patterns in Academic Versus Nonacademic Settings.

Based on IRIS Registry data, notable differences appear to exist with regard to ethnoracial groups, glaucoma severity, and diagnostic and surgical practice patterns in academic vs nonacademic settings.

Tube Versus Trabeculectomy IRIS Registry Study: 1-Year Secondary Treatment Outcomes.

The TVTtube and trabeculectomy groups had comparable 1-year IOP reduction, although trabeculectomy eyes used fewer glaucoma medications.

Intraocular Pressure after Phacoemulsification with Retained Lens Fragments in the IRIS® Registry (Intelligent Research in Sight).

The initial IOP elevation after phacoemulsification resulting in RLFs is higher than after standard cataract surgery because of an increased incidence of IOP spike.

Re: Liao et al.: Human papillomavirus infection is associated with increased risk of glaucoma: evidence in an electronic health record study(Ophthalmology. 2025;132:1161-1168).

Factors Associated with Goniotomy Outcomes in the United States: An IRIS® Registry Analysis.

In this large national cohort, several demographic and clinical factors-including higher baseline IOP, more severe glaucoma, PXG, and LTG diagnoses-were predictive of goniotomy success.

Re: Chauhan et al.: Association of primary open-angle glaucoma with diabetic retinopathy among patients with type 1 and type 2 diabetes: a large global database study. (Ophthalmology. 2024;131:827-835).