Arthur J. Sit

OCT Angiography for the Diagnosis of Glaucoma: A Report by the American Academy of Ophthalmology.

Vessel density loss associated with glaucoma can be detected by OCTA. Peripapillary, macular, and choroidal vessel density parameters may complement visual field and structural OCT measurements in the diagnosis of glaucoma.

In Vivo Noninvasive Measurement of Young's Modulus of Elasticity in Human Eyes: A Feasibility Study.

USWE is a novel noninvasive technique for measuring ocular biomechanical properties.

Netarsudil Improves Trabecular Outflow Facility in Patients with Primary Open Angle Glaucoma or Ocular Hypertension: A Phase 2 Study.

Netarsudil acts on the conventional outflow pathway, both proximal and distal, to significantly reduce IOP in POAG and OHT by improving trabecular outflow facility and decreasing EVP.

Association of a Primary Open-Angle Glaucoma Genetic Risk Score With Earlier Age at Diagnosis.

A higher dose of POAG risk alleles was associated with an earlier age at glaucoma diagnosis.

Corneal Hysteresis for the Diagnosis of Glaucoma and Assessment of Progression Risk: A Report by the American Academy of Ophthalmology.

Corneal hysteresis is lower in glaucoma patients compared with normal subjects, and lower CH is associated with an increased risk of disease progression.

The Risk of Primary Open-Angle Glaucoma Following Vitreoretinal Surgery-A Population-based Study.

The mean age was 64.7 years and the median follow-up period was 4.9 years.

Trabecular Procedures Combined with Cataract Surgery for Open-Angle Glaucoma: A Report by the American Academy of Ophthalmology.

Trabecular procedures combined with cataract surgery provide an additional mild IOP reduction over cataract surgery alone in hypertensive OAG subjects.

Central Visual Field Testing in Early Glaucoma: A Report by the American Academy of Ophthalmology.

Evidence to date does not support routine testing using 10-2 VF for patients with early glaucoma.

Selective Laser Trabeculoplasty for the Treatment of Glaucoma: A Report by the American Academy of Ophthalmology.

Based on level I evidence, SLT is an effective long-term option for the treatment of open-angle glaucoma and is equivalent to ALT.

Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets.

Collectively, testosterone metabolism pathway SNPs were consistently associated with the high-tension subtype of POAG in two datasets.

Comparison of Corneal Wave Speed and Ocular Rigidity in Normal and Glaucomatous Eyes.

Glaucomatous eyes tend to have lower ocular rigidity than healthy eyes with similar age, IOP, and axial length.

Incidence of Dementia in Patients With Open-angle Glaucoma: A Population-based Study.

The risk of developing dementia or AD was decreased in OAG patients compared with the general population.

Risk, Prevalence, and Progression of Glaucoma in Eyes With Age-Related Macular Degeneration Treated With Intravitreal Anti-Vascular Endothelial Growth Factor Injections.

Eyes treated with intravitreal anti-VEGF injections for exudative AMD did not have increased risk of developing glaucoma compared with controls.

Rates of Diplopia in Ahmed FP7, Baerveldt 250, and 350 Glaucoma Patients Compared With Medical Controls.

Patients with the larger (B350) or the higher profile plate (FP7) GDDs were more likely to experience diplopia than controls, and diplopia was attributable to the GDD in ~6% of patients with either a FP7 or a B350 GDD.

Aqueous Shunts with Extraocular Reservoir for Open-Angle Adult Glaucoma: A Report by the American Academy of Ophthalmology.

Implantation of aqueous shunts with extraocular reservoir, including valved or nonvalved devices, has been shown to be an effective strategy to lower IOP.

Surgical Advancement of Tenon's Layer During Trabeculectomy Improves Bleb Morphology.

Therefore, in our surgical practice, a small number of patients had trabeculectomy in 1 eye before implementation of this new technique, and then had trabeculectomy in the fellow eye after this technique was adopted, providing…

Eye Dynamics and Engineering Network Consortium: Baseline Characteristics of a Randomized Trial in Healthy Adults.

The current study from the EDEN Consortium describes measurement methods and data analyses with emphasis on IOP variability.

Progressive Paracentral Visual Field Loss at Low Intraocular Pressures Following LASIK.

This series suggests that additional study into the association of LASIK and glaucoma is warranted, including the potential risk contribution of diminished CH.

Single-Use Lens Compromise During Selective Laser Trabeculoplasty.

Increased laser damage to disposable SLT lenses was associated with diminished treatment effect.

A Case of Uveitis-Glaucoma-Hyphema Syndrome Related to a Hydrus Microstent.

We present a rare case of UGH syndrome related to the insertion of a Hydrus Microstent.

The Effect of Scleral Buckle Surgery on Tonographic Outflow Facility, Positional Intraocular Pressure, and Ocular Biomechanics.

Scleral buckling decreases ocular rigidity but does not affect outflow facility.

Assessing Agreement of Intraocular Pressure from Four Mechanistically Different Tonometers in the Eye Dynamics and Engineering Network Clinical Trial.

When adjusted for proparacaine's effect on IOP, 3 tonometers were equivalent between each other when determined by equivalence statistical testing with equivalence bounds ± 2 mmHg.

Delayed Onset Spontaneous Hyphema After an OMNI Surgical Procedure.

This case report describes a patient with recurrent and refractory delayed onset spontaneous hyphema after an OMNI procedure.

Objective Grading of Tonography Tracings for the Measurement of Outflow Facility.

Objective assessment of pneumatonography tracings can be performed using RMSE of a fitted line and calculation of a predicted quality score that closely matches scores given by expert graders.

CYP3A4 Poor and Intermediate Metabolizers Have a Higher Rate of Steroid-Induced Intraocular Pressure Response.

Reduced CYP3A4 phenotypes may help identify patients at a higher risk of steroid-induced IOP elevation.

Determination of the Trans-Lamina Cribrosa Pressure Difference in a Community-Based Population and its Association with Open-Angle Glaucoma.

This study establishes the baseline TLCPD in a large cohort of normal, community-based patients.

The Risk of Primary Open-Angle Glaucoma Following Vitreoretinal Surgery-A Population-based Study.

Assessing the Association of Mitochondrial Genetic Variation With Primary Open-Angle Glaucoma Using Gene-Set Analyses.

We present an effective approach for assessing the contributions of mitochondrial genetic variation to open-angle glaucoma.

A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium.

Our integrative study is the first to associate rs76481776 with POAG via elevated miR-182 expression.