Thomas Ravi

Age-related changes in and determinants of macular ganglion cell-inner plexiform layer thickness in normal Chinese adults.

Mean mGCIPL thickness showed a small age-related linear decrease with two steep drops in the fifth and seventh decades.

Progression of Primary Angle Closure Suspect to Primary Angle Closure and Associated Risk Factors: The Handan Eye Study.

We report the progression from baseline PACS to PAC/PACG after five years. And baseline mean angle width was determined to be independent predictive risk factor for the progression of angle closure.

Development of angle closure and associated risk factors: The Handan eye study.

This study reports the development from baseline open angle to angle closure after a 5-year follow-up.

Association of intraocular pressure-related factors and retinal vessel diameter with optic disc rim area in subjects with and without primary open angle glaucoma.

Reduced RA is associated with narrow CRVE and higher IOP or lower CSFP. The data supports the concurrent role of IOP-related and vascular factors in glaucomatous optic nerve damage.

Establishment and Comparison of Algorithms for Detection of Primary Angle Closure Suspect Based on Static and Dynamic Anterior Segment Parameters.

The three algorithms did not meet the requirements for population-based screening of PACS. One possible reason could be the different angle closure mechanisms in enrolled eyes.

Noninvasive evaluation of cerebrospinal fluid pressure in ocular hypertension: a preliminary study.

The wider OSASW and higher estimated CSFP in OH subjects suggest a higher orbital CSFP.

Association of Hypertriglyceridemia and Incident Glaucoma in a Rural Chinese Population: The Handan Eye Study.

Our study revealed that increased age and high TGs level, one of the baseline metabolic features, were independent risk factors for incident glaucoma.

Five-year incidence of primary glaucoma and related risk factors - The Handan eye study.

We reported the 5-year incidence of primary glaucoma in a rural Chinese population and found that older age, higher IOP, and VCDR ≥ 0.60 at baseline could help in identifying those at highest risk of disease development.

Detection of primary angleclosure suspect with different mechanisms of angle closure using multivariate prediction models.

Prediction models showed the best performance for detection of PACS with PB mechanism for AC and have potential for screening of PACS.

Comparison of Peripapillary Retinal Nerve Fiber Layer Thickness, Functional Subzones, and Macular Ganglion Cell-Inner Plexiform Layer in Differentiating Patients With Mild, Moderate, and Severe Open-angle Glaucoma.

Mean pRNFL had the best diagnostic performance in mild and severe glaucoma.

Long-term progression after laser peripheral iridotomy in Caucasian primary angle closure suspects.

Visual symptoms following iridotomy.

Re: Yu et al.: Risk of visual field progression in glaucoma patients with progressive retinal nerve fiber layer thinning (Ophthalmology. 2016;123:1201-1210).

Association between location of laser iridotomy and frequency of visual symptoms: a Bayesian learning analysis.

Dynamic Iris Changes as a Risk Factor in Primary Angle Closure Disease.

Significant differences in iris behavior in the dark compared to light in PACS, PACD, and normal eyes add to the evidence that dynamic iris change has a role in the pathogenesis of PAC in a…

Retinotopic Changes in the Gray Matter Volume and Cerebral Blood Flow in the Primary Visual Cortex of Patients With Primary Open-Angle Glaucoma.

Primary open-angle glaucoma patients demonstrate a disease severity-dependent retinotopic pattern of cortical atrophy and CBF abnormalities in the visual cortex. Cerebral blood flow may be a potential biomarker for the brain involvement in glaucoma.

Initial Treatment for Primary Angle-Closure Glaucoma in China.

The greater reduction of and more stable IOP, lower frequency of acute angle closure, decreased progression of peripheral anterior synechia and glaucoma, and the reduction of ocular complications associated with long-term use of glaucoma medications…

Re: Mwanza et al.: diagnostic performance of optical coherence tomography ganglion cell-inner plexiform layer thickness measurements in early glaucoma (Ophthalmology 2014;121:849-54).

Quantitative analysis of iris changes following mydriasis in subjects with different mechanisms of angle closure.

There are significant differences in IA and IA loss per mm of pupil change following physiologic or pharmacologic mydriasis in Chinese subjects with dissimilar dominant mechanisms for AC.

Lens surgery to treat open-angle glaucoma: triumph of hope over (evidence-based) experience.