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J GlaucomaApril 20190 citations

Autologous Partial-thickness Scleral Flap and Donor Corneal Graft in Management of Tube Erosion of Glaucoma Drainage Device.

Liu Xiongfei, Law Simon K


AI Summary

This study found that using an autologous scleral flap and donor corneal graft effectively repairs glaucoma drainage device tube erosion, offering a viable, complication-free surgical option for this challenging complication.

Abstract

Purpose

To evaluate the outcomes of autologous limbus-hinged partial-thickness scleral flap and half-moon-shaped split-thickness donor corneal allograft in management of tube erosion of glaucoma drainage device.

Methods

Consecutive patients who had undergone a limbus-hinged partial-thickness scleral flap and half-moon-shaped split-thickness corneal graft were reviewed. Primary outcome was surgical success of coverage of the exposed tube without complications or additional surgeries. Secondary outcomes were visual acuity (VA), intraocular pressure, number of glaucoma medications, surgical complications, and additional surgeries.

Results

From March 1, 2016 to August 30, 2017 (18 mo), 8 consecutive cases (7 patients) of tube erosions were included for analysis. Mean follow-up and age were 16.6±5.4 months and 74.4±15.2 years, respectively. Mean number of intraocular surgeries was 4.8±1.6 (range: 3 to 6 surgeries) and intraocular glaucoma surgeries was 2.9±1.7 (range: 1 to 6 surgeries) before tube erosion. There were no intraoperative or postoperative complications or recurrence of tube erosion in any patient. Differences between the preoperative and postoperative number of medications (2.6±1.8, 2.9±1.8, respectively; P=0.171) and intraocular pressure (12.9±6.9, 10.8±3.5 mm Hg, respectively; P=0.209) were not statistically significant. Preoperative and 3-month postoperative VA were identical in all eyes except in 1 eye that the VA improved from 20/300 to 20/70 after repair.

Conclusions

Combination of limbus-hinged partial-thickness scleral flap and half-moon-shaped split-thickness corneal allograft is a viable surgical option to repair tube erosion.


MeSH Terms

Aged, 80 and overCorneal TransplantationFemaleGlaucoma Drainage ImplantsHumansIntraocular PressureMaleMiddle AgedPostoperative ComplicationsProsthesis FailureRetrospective StudiesScleraSurgical FlapsTissue DonorsTonometry, OcularTransplantation, AutologousVisual Acuity

Key Concepts5

The combination of limbus-hinged partial-thickness scleral flap and half-moon-shaped split-thickness corneal allograft is a viable surgical option to repair tube erosion of glaucoma drainage device.

TreatmentCase seriesCase Seriesn=8 cases (7 patients)Ch27Ch41

In 8 consecutive cases (7 patients) of tube erosions treated with a limbus-hinged partial-thickness scleral flap and half-moon-shaped split-thickness corneal graft, there were no intraoperative or postoperative complications or recurrence of tube erosion.

PrognosisCase seriesCase Seriesn=8 cases (7 patients)Ch27Ch41

In 8 consecutive cases (7 patients) of tube erosions, there was no statistically significant difference between the preoperative (2.6±1.8) and postoperative (2.9±1.8) number of glaucoma medications (P=0.171) after repair with a limbus-hinged partial-thickness scleral flap and half-moon-shaped split-thickness corneal graft.

TreatmentCase seriesCase Seriesn=8 cases (7 patients)Ch28Ch41

In 8 consecutive cases (7 patients) of tube erosions, there was no statistically significant difference between the preoperative (12.9±6.9 mm Hg) and postoperative (10.8±3.5 mm Hg) intraocular pressure (P=0.209) after repair with a limbus-hinged partial-thickness scleral flap and half-moon-shaped split-thickness corneal graft.

TreatmentCase seriesCase Seriesn=8 cases (7 patients)Ch3Ch41

In 8 consecutive cases (7 patients) of tube erosions, the mean follow-up was 16.6±5.4 months and the mean age was 74.4±15.2 years.

EpidemiologyCase seriesCase Seriesn=8 cases (7 patients)Ch10Ch27

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