Chapter 27: Management of the Glaucoma Patient

Loukovaara Sirpa, Haukka Jari

This study found that postmenopausal hormone replacement therapy, particularly estrogen-only, was associated with an increased risk of developing glaucoma in women over 50.

Teng Ruiwen, Luo Jia, Zhao Peiquan et al.

A model predicts altitude-related IOP spikes post-vitrectomy with gas, finding varied safe travel intervals by gas type, offering personalized risk assessment for patients.

Kashaf Michael Saheb, Nagarajan Niranjani, Le Jimmy T et al.

This review found only 13 of 91 glaucoma patient-reported outcome measures met rigorous development standards. Clinicians should judiciously use PROMs, understanding their design and limitations to ensure meaningful patient assessment.

Rocks Madeline C, Dossantos Jason, Tran Hoang-Viet et al.

This study found OMNI canaloplasty with or without a Hydrus microstent during cataract surgery yielded comparable IOP, medication, and success rates at one year, suggesting the microstent may not add significant benefit.

Kolovos Antonia, Aung Tin, Khawaja Anthony P et al.

Polygenic risk scores (PRS) for glaucoma show promise in improving early diagnosis and predicting disease course, offering personalized risk assessment to enhance clinical management.

Cai, Yuting, Zhang, Chenguang, Dang, Pengrui et al.

This smart contact lens monitors eye pressure and automatically releases glaucoma medication when pressure is high, offering a personalized, real-time treatment solution.

Steger Jennifer S, Capó-Aponte José E, Papp Alexandra et al.

Microdrops via Nanodropper showed better IOP lowering, reduced bottle exhaustion, and fewer side effects than conventional drops, potentially improving glaucoma treatment adherence and control.

Iswarya Radhakrishnan, Haribalaganesh Ravinarayanan, Senthilkumari Srinivasan et al.

This study found transplanted trabecular meshwork stem cells reduced intraocular pressure and increased cell proliferation in a glaucoma model, suggesting a potential therapy for outflow pathway dysfunction.

Hwang Young Hoon, Lee Sharon, Kim Mijin et al.

SC-CPC effectively lowered eye pressure and medication use in Korean patients with uncontrolled glaucoma, showing promise as a useful treatment option despite some visual decline.

Realini Tony, Balasubramani G K, Kenkre Tanya et al.

The COAST trial compares standard versus low-energy SLT for new glaucoma/OHT. The abstract details the study design and baseline patient characteristics, showing a representative sample, which will clarify optimal SLT use for long-term glaucoma management.

Marin Alejandro, Quintero Maria A, Kaplan Tyler M et al.

Cordeiro M Francesca, Oddone Francesco, Mermeklieva Elena Atanasova et al.

This study found a new low-concentration bimatoprost/timolol gel is as effective as standard drops for glaucoma/OHT, offering a safe, comparable treatment option.

Kang Edward, Park Ji-Hye, Yoo Chungkwon et al.

This study found glaucomatous eyes with optic disc hemorrhage have higher stress at the lamina cribrosa-sclera interface, particularly during eye movement. This suggests biomechanical stress contributes to ODH, with age and axial length as risk factors.

Civelekler Mustafa, Citirik Mehmet

DeepSeek AI outperformed other models in generating glaucoma PubMed citations, but all AI models produced errors, highlighting the need for human verification to prevent citation inaccuracies.

Tempelhof Ortal Fogel, Reich Yael, Rachmiel Rony et al.

Face masks inconsistently affect Goldmann tonometry, causing clinically significant IOP changes (≥3 mmHg) in one-third of patients, warranting re-measurement without a mask for accurate glaucoma management.

Seresirikachorn Kasem, Chang Ta Chen Peter

Cohen Shai, Weiss Tamir, Sela Yaron et al.

An OCT-based telemedicine model for IIH management showed high agreement (87%) with in-person visits for treatment recommendations, suggesting its feasibility for remote patient care.

Mieno Hiroki, Mori Kazuhiko, Kano Kiyoshi et al.

PRESERFLO MicroShunt effectively lowered IOP and medication use in a large Japanese cohort. High preoperative medication use and prior cataract surgery were risk factors for failure, guiding patient selection.

Wu Na, Aihemaiti Xianmuseye, Sun Xinghuai et al.

In untreated glaucoma, higher corneal deformability (less stiffness) was associated with lower 24-hour intraocular pressure variation. This suggests corneal properties may influence IOP measurement and glaucoma management.