Law Simon K

Mohammadzadeh Vahid, Su Erica, Besharati Sajad, Liu Abraham, Law Simon K, Coleman Anne L et al.

A Bayesian model found central visual field points with 5-20 dB sensitivity show high variability. Excluding these points could improve glaucoma progression detection.

Demer Joseph L, Clark Robert A, Suh Soh Youn, Giaconi JoAnn A, Nouri-Mahdavi Kouros, Law Simon K et al.

Eye movements normally pump CSF around the optic nerve, but this pumping was subnormal in glaucoma and NA-AION, suggesting impaired CSF dynamics may contribute to these optic neuropathies.

Mohammadi Massood, Su Erica, Mohammadzadeh Vahid, Besharati Sajad, Martinyan Arthur, Coleman Anne L et al.

This study found that while both GCC and RNFL detect glaucoma progression, RNFL's utility diminishes in advanced disease. Clinically, GCC may be more valuable for monitoring severe glaucoma.

Su Erica, Mohammadzadeh Vahid, Mohammadi Massood, Shi Lynn, Law Simon K, Coleman Anne L et al.

A new statistical model (Bayesian HSL) more accurately tracks macular nerve fiber layer thinning in glaucoma than standard methods, enabling earlier and more efficient detection of disease progression.

Mohammadzadeh Vahid, Su Erica, Mohammadi Massood, Law Simon K, Coleman Anne L, Caprioli Joseph et al.

This study found lower diastolic blood pressure combined with higher intraocular pressure accelerates macular ganglion cell thinning in glaucoma, suggesting blood pressure management may be a therapeutic consideration.

Mohammadzadeh Vahid, Su Erica, Shi Lynn, Coleman Anne L, Law Simon K, Caprioli Joseph et al.

This study modeled longitudinal macular GCC changes in glaucoma, finding strong spatiotemporal correlations and distinct regional patterns. This improves understanding of glaucoma progression and refines predictive modeling for better patient care.

Mohammadzadeh Vahid, Su Erica, Rabiolo Alessandro, Shi Lynn, Zadeh Sepideh Heydar, Law Simon K et al.

This study found that macular Ganglion Cell Complex (GCC) thickness is the optimal OCT measure for detecting structural progression in moderate-to-severe glaucoma, despite full macular thickness showing more change.

Mahmoudinezhad Golnoush, Mohammadzadeh Vahid, Amini Navid, Delao Kevin, Zhou Bingnan, Hong Tae et al.

This study found Spectralis OCT detected macular ganglion cell thinning in glaucoma more frequently and faster than Cirrus OCT, highlighting that these devices are not interchangeable for monitoring progression.

Mohammadzadeh Vahid, Su Erica, Heydar Zadeh Sepideh, Law Simon K, Coleman Anne L, Caprioli Joseph et al.

This study developed a Bayesian model to track local macular GCC thinning via OCT. It efficiently estimates individual glaucoma progression rates, aiding early detection and management.

Robbins Laura, Goseki Toshiaki, Law Simon K, Nouri-Mahdavi Kouros, Caprioli Joseph, Coleman Anne L et al.

This study found 4% of patients developed new strabismus after Ahmed Glaucoma Valve implantation, often exotropia. This highlights a significant complication for patient counseling, comparable to larger glaucoma devices.

Law Simon K, Salazar Diana, Yu Fei, Giaconi JoAnn A, Chen Angela, Chopra Vikas et al.

Combined CyPass micro-stent and cataract surgery reduced glaucoma medications and IOP, showing 28-42% success at one year, offering a potential option for medication burden reduction.

Bonnet Clemence, Ghaffari Reza, Alkadi Turad, Law Simon K, Caprioli Joseph, Yu Fei et al.

DMEK in eyes with prior glaucoma surgery yields good long-term vision, but showed significantly higher rates of secondary graft failure and endothelial cell loss compared to eyes without prior glaucoma surgery.

Rabiolo Alessandro, Mohammadzadeh Vahid, Fatehi Nima, Morales Esteban, Coleman Anne L, Law Simon K et al.

This study compared macular OCT measures for glaucoma progression, finding ganglion cell complex (GCC) measurements best detect structural worsening across all glaucoma severities, making them optimal for monitoring deterioration.

Chen Jessica Y, Le Alan, Caprioli Joseph, Giaconi JoAnn A, Nouri-Mahdavi Kouros, Law Simon K et al.

Glaucoma patients on PGAs had less overall orbital fat, but similar anterior fat, possibly due to a narrower bony orbit, which might be a glaucoma risk factor.

Law Simon K

Mohammadzadeh Vahid, Rabiolo Alessandro, Fu Qiang, Morales Esteban, Coleman Anne L, Law Simon K et al.

This study found weak correlations between central macular OCT and visual field changes in glaucoma, with structural worsening detected more frequently. Both measurements are crucial for optimal progression detection.

Daneshvar Ramin, Yarmohammadi Adeleh, Alizadeh Reza, Henry Sharon, Law Simon K, Caprioli Joseph et al.

Baseline OCT structural measures, unlike clinical disc parameters, predicted future visual field progression in glaucoma patients. This suggests OCT is crucial for predicting glaucoma worsening.

Liu Xiongfei, Thung Elaine G, Caprioli Joseph, Law Simon K

This study found a combined cyclopexy and cryopexy technique safely and effectively repaired cyclodialysis clefts, restoring intraocular pressure and vision in most patients, making it a viable primary surgical option.

Lin Mark, Alizadeh Reza, Law Simon K

This study found combining Ahmed Glaucoma Valve with trabeculectomy revision after failed trabeculectomy provided better IOP control and reduced hypertensive phase compared to AGV alone, especially for low IOP targets.

Liu Xiongfei, Law Simon K

This study found that using an autologous scleral flap and donor corneal graft effectively repairs glaucoma drainage device tube erosion, offering a viable, complication-free surgical option for this challenging complication.

Lin Shawn R, Prapaipanich Pitchaya, Yu Fei, Law Simon K, Caprioli Joseph, Aldave Anthony J et al.

In eyes with prior glaucoma surgery, DMEK provided superior visual recovery and final acuity, plus lower secondary graft failure rates compared to DSEK, making it a better choice for these complex cases.

Nguyen Andrew H, Fatehi Nima, Romero Pablo, Miraftabi Arezoo, Kim EunAh, Morales Esteban et al.

This study found that patients of African descent had higher trabeculectomy failure rates and more bleb leaks after initial surgery with mitomycin C than European descent patients, highlighting racial disparities in surgical outcomes.

Alizadeh Reza, Akil Handan, Tan James, Law Simon K, Caprioli Joseph

Trabeculectomy effectively lowers intraocular pressure in patients with uncontrolled glaucoma after drainage device surgery, offering a viable treatment option despite potential complications like hypotony.

Romero Pablo, Hirunpatravong Pradtana, Alizadeh Reza, Kim Eun-Ah, Nouri-Mahdavi Kouros, Morales Esteban et al.

Trabeculectomy with MMC effectively lowered IOP in PACG, achieving mid-teen targets long-term. Factors like crystalline lens, no iridotomy, and high pre-op IOP increased failure risk, guiding patient selection.

Demer Joseph L, Clark Robert A, Suh Soh Youn, Giaconi JoAnn A, Nouri-Mahdavi Kouros, Law Simon K et al.

MRI of normal-tension glaucoma patients revealed abnormally increased globe retraction and optic nerve straightening during adduction, suggesting mechanical stress on the optic nerve head may contribute to glaucoma, independent of IOP.