Rabiolo Alessandro

Khaliliyeh Daniela, Jin Sangwook, Morales Esteban, Rabiolo Alessandro, de Gainza Agustina, Leyva Brayden K et al.

Numerical hypotony post-trabeculectomy with MMC is often asymptomatic. Only 20.1% developed clinical hypotony (choroidal effusion common). Intervention is mainly for symptomatic cases, with ethnicity and suture lysis influencing risk.

Lupardi Enrico, Ferri Monica, Galzignato Alice, Coutinho Catarina P, Laffi Gian Luca, Distefano Andrea et al.

Rabiolo Alessandro, Triolo Giacinto, Servillo Andrea, Khaliliyeh Daniela, Jin Sang W, Morales Esteban et al.

Glaucoma surgery success rates vary wildly based on high IOP failure criteria. These IOP-based definitions poorly reflect visual field progression, highlighting the need for standardized criteria and incorporating VF rates for meaningful comparisons.

Matarazzo Francesco, Cutolo Carlo Alberto, Rabiolo Alessandro, Figus Michele, Fea Antonio, Gandolfi Stefano et al.

Italian experts developed consensus guidelines for glaucoma virtual clinics, identifying suitable patients, essential tests, and staffing. This enhances care accessibility and streamlines workflows.

Montesano Giovanni, Rabiolo Alessandro, Ometto Giovanni, Crabb David P, Garway-Heath David F

This study found visual field progression appeared faster than structural, but a floor effect explained this; IOP similarly accelerated both, emphasizing comprehensive monitoring.

Montesano Giovanni, Crabb David P, Wright David M, Rabiolo Alessandro, Ometto Giovanni, Garway-Heath David F

Rabiolo Alessandro, Montesano Giovanni, Gazzard Gus, Caprioli Joseph, De Cillà Stefano

Petriti Bledi, Rabiolo Alessandro, Chau Kai-Yin, Williams Pete A, Montesano Giovanni, Lascaratos Gerassimos et al.

This study found that lower immune cell (PBMC) oxygen consumption is strongly linked to faster vision loss in treated glaucoma patients, suggesting it's a new biomarker for progression.

Montesano Giovanni, Crabb David P, Wright David M, Rabiolo Alessandro, Ometto Giovanni, Garway-Heath David F

This study found a novel exGaussian model more accurately estimates true glaucoma visual field progression rates than standard methods, improving clinical trial design and sample size calculations.

Rabiolo Alessandro, Montesano Giovanni, Crabb David P, Garway-Heath David F

This study found standard IOP fluctuations don't predict glaucoma progression, but mean IOP and ocular pulse amplitude might be more relevant for identifying faster progression.

Rabiolo Alessandro, Triolo Giacinto, Khaliliyeh Daniela, Jin Sang Wook, Morales Esteban, Ghirardi Alessandro et al.

This study found glaucoma surgery hypotony criteria are highly variable; numerical definitions inflate failure rates more than clinical ones, underscoring the need for standardized, clinically relevant criteria.

Rabiolo Alessandro, Toscani Rebecca, Sacchi Matteo, Destefanis Pietro, Bettin Paolo, Ciampi Carlo et al.

This study found higher intraoperative MMC concentration improved Microshunt success, while complex glaucoma types, prior surgeries, and lower baseline IOP increased failure risk, guiding patient selection.

Montesano Giovanni, Garway-Heath David F, Rabiolo Alessandro, De Moraes Carlos Gustavo, Ometto Giovanni, Crabb David P

This study found trend-based visual field analyses (LMM, TTP) are more powerful than FDA-accepted event-based methods for detecting treatment effects in glaucoma neuroprotection trials, offering more efficient clinical trial design.

De Gainza Agustina, Morales Esteban, Rabiolo Alessandro, Yu Fei, Afifi Abdelmonem A, Nouri-Mahdavi Kouros et al.

Researchers developed a "metascore" combining different glaucoma imaging measurements (HRT, OCT) into a single scale. This unifies long-term structural data from various devices, improving patient follow-up despite instrument changes.

Rabiolo Alessandro, Barton Keith, McNaught Andrew Ian

Rabiolo Alessandro, Fantaguzzi Federico, Montesano Giovanni, Brambati Maria, Sacconi Riccardo, Gelormini Francesco et al.

This study compared SD-OCT and SS-OCT for glaucoma detection. Measurements weren't directly interchangeable but were interconvertible, showing similar diagnostic accuracy. This means clinicians can use either device, potentially with conversion, for glaucoma assessment.

Bhayani Raj, Martínez de la Casa Jose Maria, Figus Michele, Klabe Karsten, Rabiolo Alessandro, Mercieca Karl

The Preserflo Microshunt effectively lowered IOP and medication use in glaucoma patients over one year, showing good safety but modest success for very low target pressures, guiding surgical selection.

Mohammadzadeh Vahid, Su Erica, Rabiolo Alessandro, Shi Lynn, Zadeh Sepideh Heydar, Law Simon K et al.

This study found that macular Ganglion Cell Complex (GCC) thickness is the optimal OCT measure for detecting structural progression in moderate-to-severe glaucoma, despite full macular thickness showing more change.

Rabiolo Alessandro, Fantaguzzi Federico, Sacconi Riccardo, Gelormini Francesco, Borrelli Enrico, Triolo Giacinto et al.

This study found that structural OCT parameters alone are superior to vascular or combined measures for diagnosing early-moderate glaucoma, meaning OCT angiography offers no additional diagnostic benefit.

Rabiolo Alessandro, Leadbetter Duncan, Kirk Jonathan, Anand Nitin

Most deep sclerectomy patients need laser goniopuncture, which effectively lowers eye pressure long-term. Higher pre-LGP IOP/meds predict failure; male gender, MMC, and longer DS-LGP interval improve success.

Rabiolo Alessandro, Leadbetter Duncan, Anand Nitin

This study on deep sclerectomy found chronic hypotony is common, but severe complications are rare and numerical hypotony doesn't always impact vision. Key risk factors for complications were identified, guiding patient selection and management.

Rabiolo Alessandro, McNaught Andrew I, Caprioli Joseph

Nouri-Mahdavi Kouros, Mohammadzadeh Vahid, Rabiolo Alessandro, Edalati Kiumars, Caprioli Joseph, Yousefi Siamak

This study found OCT structural changes, especially macular GCIPL, can predict visual field progression in moderate-advanced glaucoma with good accuracy, aiding earlier clinical intervention.

Cicinelli Maria Vittoria, Rosenblatt Amir, Grosso Domenico, Zollet Piero, Capone Luigi, Rabiolo Alessandro et al.

Prior DEX implant response predicts morphological and IOP outcomes with subsequent FAc in DMO, guiding treatment selection and anticipating IOP risk.

Rabiolo Alessandro, Mohammadzadeh Vahid, Fatehi Nima, Morales Esteban, Coleman Anne L, Law Simon K et al.

This study compared macular OCT measures for glaucoma progression, finding ganglion cell complex (GCC) measurements best detect structural worsening across all glaucoma severities, making them optimal for monitoring deterioration.