Health-related quality of life in Ahmed FP7, and Baerveldt 250 and 350 patients compared with medical controls.
Kilgore Khin P, Wang Feng, Stern Nicole C, Jamali Dogahe Sepideh, White Launia J, Khanna Cheryl L
AI Summary
This study found glaucoma drainage device patients, especially younger ones with diplopia or worse vision, had lower quality of life than medically treated controls, with no significant differences among device types.
Abstract
Purpose
To compare health-related quality of life (HRQoL) in patients with Ahmed FP7 (FP7), Baerveldt 250 (B250) and Baerveldt 350 (B350) glaucoma drainage device (GDDs), and medically treated controls.
Methods
This was a prospective cohort study from August 2017 to July 2019. The NEI 25-Item Visual Function Questionnaire (VFQ-25), the Adult Strabismus-20 questionnaire (AS-20) and the Diplopia Questionnaire were conducted ≥30 days postoperatively in GDD patients, on enrolment for controls. Age, sex, treatment type, visual acuity, mean deviation and diplopia were evaluated for association with HRQoL RESULTS: Of the 128 GDD patients enrolled, 35 (27.3%) had FP7, 32 (25.0%) had B250 and 61 (47.7%) had B350. In univariate analysis, decreased HRQoL was associated with younger age (r 2 range 0.042-0.071), diplopia (r 2 range 0.039-0.119), GDD treatment (r 2 range 0.023-0.103), lower visual acuity (r 2 range 0.021-0.215) and worse mean deviation (r 2 range 0.029-0.131). All GDD groups had lower HRQoL subscores than the controls. HRQoL scores were lower compared with controls among B350 patients for AS-20 Self-perception subscale, B250 and B350 for Reading and General Function subscales, and FP7 and B350 for VFQ-25 Visual Functioning subscale. There were no significant differences among the GDDs.
Conclusions
Glaucoma patients with a younger age, diplopia, lower visual acuity, worse mean deviation or a GDD had lower HRQoL. Those with B350 had lower self-perception scores, consistent with previous reports in the literature. This subscale was not diminished in FP7 or B250, so the decreased self-perception scores may be due to greater visibility or awareness of the B350.
MeSH Terms
Shields Classification
Key Concepts6
In a prospective cohort study of 128 glaucoma drainage device (GDD) patients and medically treated controls, decreased health-related quality of life (HRQoL) was associated with younger age (r^2 range 0.042-0.071), diplopia (r^2 range 0.039-0.119), GDD treatment (r^2 range 0.023-0.103), lower visual acuity (r^2 range 0.021-0.215), and worse mean deviation (r^2 range 0.029-0.131).
In a prospective cohort study, all glaucoma patients treated with Ahmed FP7, Baerveldt 250, and Baerveldt 350 glaucoma drainage devices had lower health-related quality of life (HRQoL) subscores compared to medically treated controls.
In a prospective cohort study, glaucoma patients with Baerveldt 350 glaucoma drainage devices had lower self-perception scores on the AS-20 questionnaire compared to medically treated controls, while this subscale was not diminished in patients with Ahmed FP7 or Baerveldt 250.
In a prospective cohort study, glaucoma patients with Baerveldt 250 and Baerveldt 350 glaucoma drainage devices had lower Reading and General Function subscales of health-related quality of life compared to medically treated controls.
In a prospective cohort study, glaucoma patients with Ahmed FP7 and Baerveldt 350 glaucoma drainage devices had lower VFQ-25 Visual Functioning subscale scores compared to medically treated controls.
In a prospective cohort study of 128 glaucoma patients who received Ahmed FP7, Baerveldt 250, or Baerveldt 350 glaucoma drainage devices, there were no significant differences in health-related quality of life scores among the different glaucoma drainage devices.
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