From Conventional Angle Surgery to 360-Degree Trabeculotomy in Pediatric Glaucoma.
Berger Osvaldo, Mohamed-Noriega Jibran, Low Sancy, Daniel Moritz C, Petchyim Sakaorat, Papadopoulos Maria, Brookes John
AI Summary
This study found 360-degree microcatheter trabeculotomy (MCT) for pediatric glaucoma achieved significantly higher success rates and fewer reoperations than conventional angle surgery, suggesting MCT is a superior treatment option.
Abstract
Purpose
To describe the transition from conventional angle surgery (CAS), trabeculotomy with rigid probe or goniotomy, to 360-degree trabeculotomy assisted with microcatheter (MCT).
Design
Retrospective comparative interventional case series.
Methods
Review of consecutive children with glaucoma undergoing angle surgery, including cases with previous surgery, from January 2012 until March 2018 at Moorfields Eye Hospital. Main outcome measure was success rate, defined as intraocular pressure (IOP) ≤21 mm Hg with a minimum of 20% of IOP reduction and no further glaucoma surgery (complete success: without the need of glaucoma drops; qualified success: drops were needed to keep the IOP under control).
Results
Among the 106 eyes (77 patients) included were 54 MCT and 52 CAS eyes. At last visit, after a single surgery, qualified success was 85% (46 eyes) in MCT and 37% (19 eyes) in CAS. Complete success was 69% (37 cases) in MCT and 23% (12 cases) in CAS. The mean (95% confidence interval) change in axial length after surgery was -0.03 mm (-0.34 to 0.40) for MCT and +1.35 mm (-0.64 to 1.62) for CAS (P < .001). The percentage of IOP reduction was 52.1% in MCT and 45.5% in CAS (P = .1616). Further glaucoma surgery was required in 5.5% (3) in MCT and 63.4% (33) in CAS. At 1 year, 94.3% of MCT cases achieved qualified success compared to 34.6% of CAS (P < .0001). No significant complications were found on either group.
Conclusion
MCT achieved better results with significantly lower reoperation rates. The transition from CAS to MCT can be easily achieved, even in difficult cases or those previously operated.
MeSH Terms
Shields Classification
Key Concepts5
At last visit, after a single surgery, qualified success was 85% (46 eyes) in 360-degree trabeculotomy assisted with microcatheter (MCT) and 37% (19 eyes) in conventional angle surgery (CAS) for pediatric glaucoma.
Complete success was 69% (37 cases) in 360-degree trabeculotomy assisted with microcatheter (MCT) and 23% (12 cases) in conventional angle surgery (CAS) for pediatric glaucoma.
The mean (95% confidence interval) change in axial length after surgery was -0.03 mm (-0.34 to 0.40) for 360-degree trabeculotomy assisted with microcatheter (MCT) and +1.35 mm (-0.64 to 1.62) for conventional angle surgery (CAS) in pediatric glaucoma (P < .001).
Further glaucoma surgery was required in 5.5% (3) of eyes treated with 360-degree trabeculotomy assisted with microcatheter (MCT) and 63.4% (33) of eyes treated with conventional angle surgery (CAS) in pediatric glaucoma.
At 1 year, 94.3% of 360-degree trabeculotomy assisted with microcatheter (MCT) cases achieved qualified success compared to 34.6% of conventional angle surgery (CAS) cases in pediatric glaucoma (P < .0001).
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