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Section II · Clinical Forms
Shields' Textbook of Glaucoma, 6th edition
Showing 1–20 of 617 articles
Papageorgiou Eleni, Toumasis Panagiotis N, Lazari Katerina et al.
OCT is a vital non-invasive tool in pediatric ophthalmology, providing structural insights into ocular development and guiding diagnosis and management across diverse eye diseases, even in uncooperative children.
Yazdani Shahin, Einollahi Neda, Doozandeh Azadeh et al.
This study found fibrous ingrowth into Ahmed Glaucoma Valves causes failure. Removing it during revision surgery effectively restores function and improves IOP, highlighting its importance in managing failed shunts.
Dhiman Shweta, Sinha Nidhi, Behera Madhusmita
Abbas Johar, Haider Faseeh, Arooj Hajira et al.
This meta-analysis found 360-degree trabeculotomy offers superior IOP reduction, fewer medications, and higher success rates than traditional angle surgery for primary congenital glaucoma, improving patient outcomes.
Cohen Samuel A, Kalavar Meghana, Sridhar Jayanth
This study synthesized surgical advances for Marfan ocular complications, finding improved outcomes but persistent high risks. Individualized planning and long-term surveillance are crucial for these patients.
Papageorgiou Eleni, Grivea Ioanna, Androudi Sofia
Jiang Jinyun, Hu Yin, Zhu Yingting et al.
This study found RGPCLs significantly improved visual acuity and contrast sensitivity more than spectacles in children post-PCG surgery, suggesting RGPCLs are a superior rehabilitation option.
Elhusseiny Abdelrahman M, Shaarawy Tarek
This review found novel implants for childhood glaucoma (e.g., PRESERFLO, PGI) show promising mid-term efficacy and safety, especially for refractory cases, but require more long-term comparative studies.
Wiggs Janey L
Glaucoma genetics research reveals numerous genes and variants, enabling genetic testing for childhood glaucoma and polygenic risk scores for adult forms, paving the way for personalized screening and care.
Liu Cindy Yue-Ying, Lee Allister Sebastian, Chiang Mark Yu-Ming
This 10-year study found Baerveldt glaucoma drainage devices effectively control IOP long-term in Australian children, especially post-cataract surgery, offering a reliable option for refractory childhood glaucoma.
Liu Yong, Gong Di, Dang Kuanrong et al.
This meta-analysis found next-generation sequencing identified genetic causes in 26.2% of primary glaucoma cases, with subtype-specific strategies (e.g., WES for PCG, panel for PACG) proving most effective for diagnosis.
Fieß Achim, Gißler Sandra, Grabitz Stephanie et al.
This study found prematurity and perinatal issues lead to thinner optic nerve layers and larger cups in children, indicating a need for careful glaucoma monitoring in this high-risk group.
Estrela Tais, Jeon-Chapman Jacqueline, Zhang Jia Jia et al.
Children with optic disc drusen show significant, faster RNFL thinning than glaucoma suspects. This helps clinicians identify rapid progressors and other optic nerve issues.
Sheheitli Huda, Brandt James, Grajewski Alana et al.
This study found that early visual acuity, intraocular pressure, media opacity, and nystagmus predict long-term outcomes in childhood glaucoma, aiding better prognosis and management.
Lucchino Luca, Vaccaro Sabrina, Romano Vito
Koonapareddy Sai Sivani, Gorenka Sneha Pranahitha, Ramappa Muralidhar
Rickels Kaersti L, Chauhan Muhammad Z, Dagi Linda R et al.
Childhood glaucoma significantly increases strabismus risk (7-14x higher than controls), with younger age, nystagmus, and amblyopia further elevating risk, highlighting the need for vigilance.
Elwehidy Ahmed Samy, Elhofi AbdElhamid Shaker, Abdelkader Amr Mohammed Elsayed et al.
This study found two surgical techniques, GATT and AVCST, similarly and significantly lowered eye pressure in primary congenital glaucoma over two years, with comparable safety. Both are effective options for children.
Hu Kun, Zhang Yu, Chen Wan et al.
This study found that secondary IOL implantation in children aged 2-6 years yields comparable vision, but glaucoma risk increases with older implantation age, guiding optimal timing for pediatric cataract management.
Groth Sylvia L, Kuchtey Rachel W
Optical coherence tomography (OCT) provides structural information that facilitates early diagnosis, informs assessment of disease severity, guides management decisions, and enables longitudinal follow-up across pediatric eye diseases, including prematurity-related pathology, congenital optic disc anomalies, foveal hypoplasia, optic neuropathies, glaucoma, retinal vascular and inflammatory disorders, inherited retinal dystrophies, ocular tumors, and neuro-ophthalmic conditions.
Parafoveal degeneration of the outer retinal layers was observed in 59% of patients with genetically confirmed Mucopolysaccharidosis type III (n = 27, median age 6.5 years, range 1-16 years) in a retrospective monocenter case series.
Foveal thickening of the external limiting membrane was noted in 67% of patients with genetically confirmed Mucopolysaccharidosis type III (n = 27, median age 6.5 years, range 1-16 years) in a retrospective monocenter case series.
One patient with Mucopolysaccharidosis type IIIA (out of 16 MPS IIIA patients) showed severe foveal atrophy, and another presented with foveal intraretinal fluid accumulation, in a retrospective monocenter case series of 27 patients with genetically confirmed MPS III.
Quantitative retinal thickness analysis in 27 patients with genetically confirmed Mucopolysaccharidosis type III (median age 6.5 years, range 1-16 years) showed median values at the lower end of the reference spectrum in the inner perifoveal ring and below the normal range in the outer perifoveal ring, with no distinct pattern distinguishing subtypes or phenotypes, in a retrospective monocenter case series.
Retinal nerve fiber layer (RNFL) thickness was unremarkable in all 27 patients with genetically confirmed Mucopolysaccharidosis type III (median age 6.5 years, range 1-16 years) in a retrospective monocenter case series.
In a posthoc cohort analysis from a multicenter randomized controlled trial in the United States (NCT00212134) involving 110 participants with unilateral congenital cataract who underwent cataract surgery between 2004 and 2007 and were followed for 10.5 years, subjects diagnosed with glaucoma had an anterior chamber depth (ACD) of 2.76 ± 0.48 mm compared to 3.08 ± 0.38 mm among subjects without glaucoma or glaucoma suspect (mean difference = 0.32 mm, P = .003).
In a posthoc cohort analysis from a multicenter randomized controlled trial in the United States (NCT00212134) involving 110 participants with unilateral congenital cataract who underwent cataract surgery between 2004 and 2007 and were followed for 10.5 years, logistic regression models found shallower anterior chamber depth (ACD) was a strong predictor of glaucoma (OR 5.8 [1.8, 18.9], P = .004) at 10.5 years following congenital cataract surgery.
In a posthoc cohort analysis from a multicenter randomized controlled trial in the United States (NCT00212134) involving 110 participants with unilateral congenital cataract who underwent cataract surgery between 2004 and 2007 and were followed for 10.5 years, other factors such as shorter axial length (OR 1.0 [0.7, 1.4], P = .9), thinner lens (OR 1.5 [0.7, 3.1], P = .3), decreased corneal diameter (OR 1.6 [0.95, 2.9], P = .08), and younger age (OR 1.01 [1.0, 1.02], P = .04) were not as strong predictors of glaucoma compared to shallower anterior chamber depth.
A posthoc cohort analysis from a multicenter randomized controlled trial (NCT00212134) included 114 participants with unilateral congenital cataract who underwent cataract surgery between 2004 and 2007 and were followed for 10.5 years as part of the Infant Aphakia Treatment Study, with 110 participants analyzed and 88 having at least one biometry measurement available.
In a posthoc cohort analysis from a multicenter randomized controlled trial in the United States (NCT00212134) involving 110 participants with unilateral congenital cataract who underwent cataract surgery between 2004 and 2007 and were followed for 10.5 years, overall, 41% of the cohort was diagnosed as glaucoma or glaucoma suspect by study endpoint.
The prevalence of primary congenital glaucoma (PCG) was significantly higher in patients with fibrous ingrowth (FI-CSR group) (8/12 [66.7%]) compared to those without abnormal ingrowth (CSR group) (11/28 [39.3%] cases, P < 0.001) undergoing capsulectomy shunt revision (CSR) for failed Ahmed Glaucoma Valves (AGVs).