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Section II · Clinical Forms

Chapter 12: Pupillary Block Glaucomas

Shields' Textbook of Glaucoma, 6th edition

Showing 1–20 of 1,060 articles

18.
Review

Controversies, consensuses, and guidelines for acute primary angle closure attack (APACA) by the Asia-Pacific Glaucoma Society (APGS) and the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO).

Chan Poemen P, Zhang Xiulan, Aung Tin et al.

Asia Pac J Ophthalmol (Phila)Jul 20255 citations

Experts established consensus on acute angle closure attack (APACA) management, recommending iridoplasty, paracentesis, pupilloplasty for rapid IOP reduction, and earlier phacoemulsification to prevent vision loss.

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PreserFlo™ MicroShunt implantation significantly reduced mean intraocular pressure (IOP) from 24.29±6.05 mmHg to 17.95±8.22 mmHg (P < 0.001) in 34 eyes from 27 children (mean age 4.9 ± 3.6 y) with refractory childhood glaucoma.

TreatmentCohortRetrospective studyn=34 eyes from 27 patients

PreserFlo™ MicroShunt implantation significantly reduced mean IOP-lowering medication numbers from 3.0±0.0 to 0.9±1.3 (P < 0.001) in 34 eyes from 27 children (mean age 4.9 ± 3.6 y) with refractory childhood glaucoma.

TreatmentCohortRetrospective studyn=34 eyes from 27 patients

Overall success of PreserFlo™ MicroShunt implantation was 61.70% in 34 eyes from 27 children with refractory childhood glaucoma, with 50% achieving complete success (IOP <21 mmHg and ≥25% IOP reduction without medications) at an average follow-up time of 13.92±4.85 months.

TreatmentCohortRetrospective studyn=34 eyes from 27 patients

The survival rates of PreserFlo™ MicroShunt implantation in refractory childhood glaucoma declined to 53% at 12 months and 33% at 24 months in 34 eyes from 27 children.

PrognosisCohortRetrospective studyn=34 eyes from 27 patients

The risk of endophthalmitis was significantly higher for pediatric versus adult patients following cataract surgery (P = 0.014), with an incidence of 0.11% (1 case per 871) in pediatric patients and 0.038% (1 case per 2652) in adult patients.

Comparative EffectivenessCohortRetrospective clinical cohort studyn=17,457,881 procedures

Eyes with previous acute primary angle closure (APAC) demonstrated marked reduction in peripapillary vessel density (VD) compared with primary angle closure suspects (PACS) and age-sex-matched healthy controls.

PrognosisCross-sectionalCross-sectional studyn=Resolved APAC, primary angle closure suspects (PACS), and age-sex-matched healthy controls

Macular vessel density (VD) was less affected in eyes with previous acute primary angle closure (APAC) compared to peripapillary VD.

PrognosisCross-sectionalCross-sectional studyn=Resolved APAC eyes

Optic nerve head (ONH) vessel density (VD) positively correlated with structural parameters in eyes with previous acute primary angle closure (APAC).

PrognosisCross-sectionalCross-sectional studyn=Resolved APAC eyes

Early primary angle closure glaucoma (PACG) patients (n=86 eyes) exhibited thicker choroidal thickness (CT) and higher choroidal vascularity index (CVI) in all macular regions compared with healthy controls (n=79 eyes) (all P <0.05).

DiagnosisCross-sectionalCross-sectional Studyn=86 early PACG patients (86 eyes) and 79 healthy individuals (79 eyes)

Increased subfoveal choroidal thickness (CT) and choroidal vascularity index (CVI) were associated with younger age, primary angle closure glaucoma (PACG) diagnosis, and/or shorter axial length (all P <0.05) in early PACG patients (n=86 eyes) and healthy controls (n=79 eyes).

PrognosisCross-sectionalCross-sectional Studyn=86 early PACG patients (86 eyes) and 79 healthy individuals (79 eyes)

After adjusting for age and/or axial length, subfoveal choroidal thickness (CT) and choroidal vascularity index (CVI) remained significantly higher in early primary angle closure glaucoma (PACG) patients (n=86 eyes) than in healthy controls (n=79 eyes) (both P <0.01).

DiagnosisCross-sectionalCross-sectional Studyn=86 early PACG patients (86 eyes) and 79 healthy individuals (79 eyes)

In early primary angle closure glaucoma (PACG) patients (n=86 eyes), the mean choroidal thickness (CT) in the inferior nasal and inferior temporal peripapillary regions was thicker than that of healthy controls (n=79 eyes) (both P <0.05).

DiagnosisCross-sectionalCross-sectional Studyn=86 early PACG patients (86 eyes) and 79 healthy individuals (79 eyes)