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J GlaucomaMay 20214 citations

Bilateral Acute Angle Closure in a Pediatric Patient Taking Lisdexamfetamine Dimesylate (Vyvanse).

Davanian Arash M, Fitzpatrick John C, Tran Duy P, Korducki John P, Groth Sylvia L


AI Summary

A 14-year-old on Vyvanse developed bilateral acute angle closure, which resolved upon discontinuing the medication. This highlights a rare but critical drug-induced glaucoma risk in pediatric patients.

Abstract

Attention-deficit/hyperactivity disorder is commonly treated with amphetamines as first line therapy. Rare case reports have shown amphetamines are associated with open angle glaucoma. We report a rare case of a 14-year-old male who presented with bilateral acute angle closure presumed to be related to his use of lisdexamfetamine dimesylate (Vyvanse). The patient's medication was discontinued which resulted in complete resolution of angle closure.


MeSH Terms

AdolescentCentral Nervous System StimulantsChildDextroamphetamineGlaucoma, Open-AngleHumansIntraocular PressureLisdexamfetamine DimesylateMaleTreatment Outcome

Key Concepts4

A 14-year-old male presented with bilateral acute angle closure presumed to be related to his use of lisdexamfetamine dimesylate (Vyvanse).

DiagnosisCase seriesCase Reportn=1 pediatric patientCh13

Discontinuation of lisdexamfetamine dimesylate (Vyvanse) resulted in complete resolution of angle closure in a 14-year-old male with bilateral acute angle closure.

TreatmentCase seriesCase Reportn=1 pediatric patientCh13Ch28

Amphetamines are commonly used as first-line therapy for attention-deficit/hyperactivity disorder.

TreatmentExpert OpinionCase Reportn=1 pediatric patientCh28

Rare case reports have shown amphetamines are associated with open angle glaucoma.

EpidemiologyCase seriesCase Reportn=1 pediatric patientCh10Ch12

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