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J GlaucomaMarch 20220 citations

Repeatability of Corneal Hysteresis Measurements in Glaucoma Patients During Routine Follow Up and After Cataract Surgery.

Zehavi-Dorin Tzukit, Kutzscher Anne E, Badr Mai, Mora Marta, Shyu Yennie, Porco Travis C, Stamper Robert L


AI Summary

Corneal hysteresis in glaucoma patients is stable during routine follow-up and after cataract surgery, suggesting post-op IOP changes aren't due to this biomechanical property.

Abstract

Prcis: Corneal hysteresis (CH) measurements are relatively stable during routine follow up of glaucoma patients over an intermediate time frame. Cataract surgery does not change the CH significantly after an average follow up of 6 months.

Purpose

The aim was to assess the repeatability of CH measurements in glaucoma patients over time, during routine follow up and after cataract surgery.

Materials and methods

Retrospective analysis of patients records in a glaucoma clinic where routine measurements by the Ocular Response Analyzer were done. Patients with at least 2 CH measurements were included. Repeatability was assessed using the intraclass correlation coefficient (ICC).

Results

A total of 164 eyes (87 patients) were included. Twenty-eight of them had measurements before and after cataract surgery with mean follow up time of 29.64±9.63 weeks. There was no evidence for a difference in CH between the before and after cataract surgery measurements (ICC=0.79, 95% confidence interval: 0.60-0.89). In the remaining 136 eyes, without any surgical treatment between measurements, there was moderate agreement among the repeated CH measurements (ICC=0.64, 95% confidence interval: 0.61-0.82) with mean time of 32.06±25.32 weeks between first and last measurement.

Conclusion

CH measurements in glaucoma patients were repeatable over a 6-month period during routine follow up or following cataract surgery. These findings suggest that the intraocular pressure reduction following cataract surgery is unlikely to be because of a change in this biomechanical property.


MeSH Terms

CataractFollow-Up StudiesGlaucomaHumansIntraocular PressureRetrospective Studies

Key Concepts4

Corneal hysteresis (CH) measurements in glaucoma patients were repeatable over a 6-month period during routine follow up or following cataract surgery.

PrognosisCohortRetrospective Cohort Studyn=164 eyes (87 patients)Ch3Ch28Ch45

There was no evidence for a difference in corneal hysteresis (CH) between before and after cataract surgery measurements in glaucoma patients (ICC=0.79, 95% confidence interval: 0.60-0.89) with a mean follow-up time of 29.64 +/- 9.63 weeks.

PrognosisCohortRetrospective Cohort Studyn=28 eyes before and after cataract sur…Ch3Ch28Ch45

In glaucoma patients without any surgical treatment between corneal hysteresis (CH) measurements, there was moderate agreement among the repeated CH measurements (ICC=0.64, 95% confidence interval: 0.61-0.82) with a mean time of 32.06 +/- 25.32 weeks between the first and last measurement.

PrognosisCohortRetrospective Cohort Studyn=136 eyes without surgical treatmentCh3Ch28

The findings suggest that the intraocular pressure reduction following cataract surgery is unlikely to be because of a change in corneal hysteresis, a biomechanical property.

MechanismCohortRetrospective Cohort Studyn=164 eyes (87 patients)Ch3Ch28Ch45

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