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Invest Ophthalmol Vis SciApril 20253 citations

Absolute Risks and Decision Tools for Communicating the Risks of Visual Impairment From Myopia-Related Diseases.

Dow Emma, Kearney Stephanie, Day Mhairi


AI Summary

This study quantified absolute risks of visual impairment from myopia-related diseases, finding higher risks with increasing myopia, especially in East Asian populations, aiding patient counseling on myopia management.

Abstract

Purpose

The risks of developing myopia complications are frequently reported in relative terms, which can be misleading. This study provides absolute risk estimates of visual impairment (VI) from myopia-related diseases.

Methods

A critical integrative review provided data on frequency of myopic macular degeneration (MMD), primary open-angle glaucoma (POAG), rhegmatogenous retinal detachment (RRD), and associated VI in predominantly White and East Asian populations. The absolute risks of persons over 40 years of age with no myopia, low myopia (-2.00 D), or high myopia (-6.00 D) developing VI from each myopia-related disease were calculated by multiplying the proportion of each refractive group with the disease by the rate of VI. The sum of the risks of VI from MMD, POAG, and RRD provided an estimate of VI risk from any of these three myopia-related diseases in adults over 40 years old.

Results

VI from MMD, POAG, or RRD combined is expected in 0.4 in 100, 1.4 in 100, and 6.8 in 100 of White persons with no myopia, low myopia, or high myopia, respectively. The same risks in an East Asian population are 0.5 in 100, 2.4 in 100 and 10.3 in 100 in persons with no myopia, low myopia, or high myopia, respectively.

Conclusions

Absolute risks are provided to enable balanced discussions of the future risk that a child may have in developing VI from myopia-related diseases when considering myopia management. These estimates should be put into context using decision tools and balanced statements providing information on the likelihood of both developing VI and not developing VI.


MeSH Terms

HumansMyopiaVision DisordersGlaucoma, Open-AngleRisk AssessmentMacular DegenerationRetinal DetachmentRisk FactorsDecision Support TechniquesAdult

Key Concepts6

Visual impairment (VI) from myopic macular degeneration (MMD), primary open-angle glaucoma (POAG), or rhegmatogenous retinal detachment (RRD) combined is expected in 0.4 in 100 White persons over 40 years of age with no myopia.

PrognosisReviewCritical Integrative Reviewn=Data from predominantly White and Eas…Ch7Ch10Ch12

Visual impairment (VI) from myopic macular degeneration (MMD), primary open-angle glaucoma (POAG), or rhegmatogenous retinal detachment (RRD) combined is expected in 1.4 in 100 White persons over 40 years of age with low myopia (-2.00 D).

PrognosisReviewCritical Integrative Reviewn=Data from predominantly White and Eas…Ch7Ch10Ch12

Visual impairment (VI) from myopic macular degeneration (MMD), primary open-angle glaucoma (POAG), or rhegmatogenous retinal detachment (RRD) combined is expected in 6.8 in 100 White persons over 40 years of age with high myopia (-6.00 D).

PrognosisReviewCritical Integrative Reviewn=Data from predominantly White and Eas…Ch7Ch10Ch12

Visual impairment (VI) from myopic macular degeneration (MMD), primary open-angle glaucoma (POAG), or rhegmatogenous retinal detachment (RRD) combined is expected in 0.5 in 100 East Asian persons over 40 years of age with no myopia.

PrognosisReviewCritical Integrative Reviewn=Data from predominantly White and Eas…Ch7Ch10Ch12

Visual impairment (VI) from myopic macular degeneration (MMD), primary open-angle glaucoma (POAG), or rhegmatogenous retinal detachment (RRD) combined is expected in 2.4 in 100 East Asian persons over 40 years of age with low myopia (-2.00 D).

PrognosisReviewCritical Integrative Reviewn=Data from predominantly White and Eas…Ch7Ch10Ch12

Visual impairment (VI) from myopic macular degeneration (MMD), primary open-angle glaucoma (POAG), or rhegmatogenous retinal detachment (RRD) combined is expected in 10.3 in 100 East Asian persons over 40 years of age with high myopia (-6.00 D).

PrognosisReviewCritical Integrative Reviewn=Data from predominantly White and Eas…Ch7Ch10Ch12

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