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Graefes Arch Clin Exp OphthalmolFebruary 201735 citations

Glaucoma drainage device surgery in children and adults: a comparative study of outcomes and complications.

Mandalos Achilleas, Sung Velota


AI Summary

This study compared glaucoma drainage device outcomes in children and adults, finding similar overall failure rates but different complication profiles and timing, emphasizing tailored postoperative vigilance.

Abstract

Purpose

To compare the postoperative outcomes and complications of glaucoma drainage device (GDD) surgery in pediatric (<18 years old) and adult patients.

Methods

Retrospective, comparative study including all patients who underwent Baervedlt or Molteno device surgery by the same surgeon. Success criteria included postoperative intraocular pressure (IOP) between 6 and 21 mmHg and a 20% reduction from baseline.

Results

Fifty-two children (69 eyes) and 130 adults (145 eyes) were included. Mean IOP and number of medications were significantly reduced postoperatively in both groups. Overall failure rate was similar in children and adults. However, GDD failed earlier in adults than in children. Hypotony was the most common complication in both groups in the first 6 months postoperatively. Later on, bleb encapsulation was more frequent in children, while corneal decompensation tended to be more frequent and occurred earlier in adults. Children also had a higher rate of infectious endophthalmitis and required tube repositioning more frequently than adults.

Conclusions

GDD surgery presents different postoperative challenges in children and adults, and the surgeon should remain vigilant for complications throughout the postoperative period, especially for signs of endophthalmitis or bleb encapsulation in pediatric patients. On the other hand, adults may be more prone to early corneal decompensation.


MeSH Terms

AdultChildFemaleFollow-Up StudiesGlaucomaGlaucoma Drainage ImplantsHumansIntraocular PressureMaleMiddle AgedOcular HypotensionPostoperative ComplicationsRetrospective StudiesTreatment OutcomeVisual AcuityYoung Adult

Key Concepts5

The overall failure rate of glaucoma drainage device (GDD) surgery was similar in children (52 children, 69 eyes) and adults (130 adults, 145 eyes) in a retrospective comparative study.

Comparative EffectivenessCohortRetrospective Comparative Studyn=52 children (69 eyes) and 130 adults …Ch42Ch43

Glaucoma drainage device (GDD) surgery failed earlier in adults than in children in a retrospective comparative study of 52 children (69 eyes) and 130 adults (145 eyes).

PrognosisCohortRetrospective Comparative Studyn=52 children (69 eyes) and 130 adults …Ch42Ch43

Hypotony was the most common complication in both children and adults in the first 6 months postoperatively following glaucoma drainage device (GDD) surgery, as observed in a retrospective comparative study of 52 children (69 eyes) and 130 adults (145 eyes).

PrognosisCohortRetrospective Comparative Studyn=52 children (69 eyes) and 130 adults …Ch42Ch43

Bleb encapsulation was more frequent in children, while corneal decompensation tended to be more frequent and occurred earlier in adults, following glaucoma drainage device (GDD) surgery in a retrospective comparative study of 52 children (69 eyes) and 130 adults (145 eyes).

PrognosisCohortRetrospective Comparative Studyn=52 children (69 eyes) and 130 adults …Ch42Ch43

Children had a higher rate of infectious endophthalmitis and required tube repositioning more frequently than adults after glaucoma drainage device (GDD) surgery, according to a retrospective comparative study of 52 children (69 eyes) and 130 adults (145 eyes).

PrognosisCohortRetrospective Comparative Studyn=52 children (69 eyes) and 130 adults …Ch42Ch43

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