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J GlaucomaFebruary 20177 citations

Evaluation of Corneal Deformation Parameters Provided by the Corvis ST Tonometer After Trabeculectomy.

Zong Yuan, Wu Na, Fu Zhixuan, Kong Xiangmei


AI Summary

Corvis ST corneal deformation parameters change significantly after trabeculectomy, correlating with IOP reduction and axial length changes. This suggests its utility for monitoring IOP normalization post-glaucoma surgery.

Abstract

Purpose

The aims of this study were to evaluate how the corneal deformation parameters provided by the Corvis ST tonometer (CST) were influenced by pressure-lowering ocular surgery, and to determine the correlations of intraocular pressure (IOP) and axial length (AL) with CST corneal deformation parameters.

Methods

This prospective 1-month study enrolled 22 subjects (22 eyes) who underwent trabeculectomy combined with mitomycin C. The corneal deformation parameters were measured using the CST. IOP was measured before and after surgery by a Goldmann applanation tonometer and the CST. The central corneal thickness and AL were also recorded. The correlations of the corneal deformation parameters with central corneal thickness, AL, and IOP changes were determined by linear regression analysis.

Results

IOP decreased significantly after surgery. AL was significantly shorter at 1 week after surgery. There were significant changes in the CST parameters time 1, velocity 1, velocity 2, peak distance highest concavity, and deformation amplitude highest concavity at 1 week and 1 month after surgery and in time highest concavity at 1 week after surgery. The change in time 1 was significantly correlated with preoperative IOP and the IOP reductions, and was positively correlated with the decrease in AL at 1 week. The increase in velocity 1 was negatively correlated with preoperative IOP, and IOP reductions. The change in time highest concavity was negatively correlated with IOP before surgery and the decrease in IOP at 1 week.

Conclusion

CST is a good choice for measuring IOP, especially when aiming for normalization of IOP after glaucoma surgery.


MeSH Terms

AdultAgedAxial Length, EyeCorneaElasticityFemaleGlaucoma, Angle-ClosureGlaucoma, Open-AngleHumansIntraocular PressureMaleMiddle AgedProspective StudiesTonometry, OcularTrabeculectomy

Key Concepts6

Intraocular pressure (IOP) decreased significantly after trabeculectomy combined with mitomycin C in 22 subjects (22 eyes).

TreatmentCohortProspective Cohort Studyn=22 subjects (22 eyes)Ch28Ch41

Axial length (AL) was significantly shorter at 1 week after trabeculectomy combined with mitomycin C in 22 subjects (22 eyes).

MechanismCohortProspective Cohort Studyn=22 subjects (22 eyes)Ch28Ch41

The Corvis ST tonometer (CST) parameters time 1, velocity 1, velocity 2, peak distance highest concavity, and deformation amplitude highest concavity showed significant changes at 1 week and 1 month after trabeculectomy combined with mitomycin C in 22 subjects (22 eyes).

DiagnosisCohortProspective Cohort Studyn=22 subjects (22 eyes)Ch3Ch41

The change in Corvis ST tonometer (CST) parameter time 1 was significantly correlated with preoperative IOP and IOP reductions, and was positively correlated with the decrease in axial length at 1 week after trabeculectomy combined with mitomycin C in 22 subjects (22 eyes).

DiagnosisCohortProspective Cohort Studyn=22 subjects (22 eyes)Ch3Ch41

The increase in Corvis ST tonometer (CST) parameter velocity 1 was negatively correlated with preoperative IOP and IOP reductions after trabeculectomy combined with mitomycin C in 22 subjects (22 eyes).

DiagnosisCohortProspective Cohort Studyn=22 subjects (22 eyes)Ch3Ch41

The Corvis ST tonometer (CST) is a good choice for measuring IOP, especially when aiming for normalization of IOP after glaucoma surgery.

DiagnosisExpert OpinionProspective Cohort Studyn=22 subjects (22 eyes)Ch3Ch28

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