Bacon D R

Orgül S, Cioffi G A, Bacon D R, Van Buskirk E M

Chronic endothelin-1 delivery to primate optic nerves significantly reduced blood flow, creating a novel model for studying hemodynamic contributions to optic neuropathies like glaucoma.

Orgül S, Mansberger S, Bacon D R, Van Buskirk E M, Cioffi G A

Topical beta-blockers (timolol, betaxolol) in rabbits showed no observable optic nerve blood vessel constriction. This suggests these glaucoma medications don't directly impair optic nerve blood flow, which is clinically relevant for patient management.

Sugiyama K, Bacon D R, Morrison J C, Van Buskirk E M

Rabbit optic nerve head blood supply primarily comes from short posterior ciliary arteries forming an incomplete circle, with pial and retinal arteries also contributing, revealing its complex vascular architecture.

Acott T S, Samples J R, Bradley J M, Bacon D R, Bylsma S S, Van Buskirk E M

Laser trabeculoplasty stimulates anterior trabecular cells to divide, and these new cells migrate to repopulate laser-damaged sites. This suggests a cellular repair mechanism for glaucoma treatment.