Drance S M

Broadway D C, Nicolela M T, Drance S M

Nicolela M T, Drance S M, Broadway D C, Chauhan B C, McCormick T A, LeBlanc R P

Clinicians showed good intraobserver agreement and reasonable interobserver agreement for classifying glaucoma optic disk patterns, which generally remained stable over time, suggesting clinical utility.

Anderson D R, Drance S M, Schulzer M

This study found that untreated normal-tension glaucoma progresses slowly in many, with about half showing localized visual field loss within 7 years, but often with minimal impact on overall vision.

Anderson D R, Chauhan B, Johnson C, Katz J, Patella V M, Drance S M

Graham S L, Drance S M

Studying glaucoma patients, researchers found greater nocturnal blood pressure dips were linked to visual field progression despite good IOP control, suggesting nocturnal hypotension is an additional glaucoma risk factor.

Drance S M

Broadway D C, Nicolela M T, Drance S M

This study found distinct POAG subgroups based on optic disk appearance, correlating with risk factors and visual field damage. Objective classification could improve diagnosis and management.

Drance S M

This study found betaxolol, timolol, and pilocarpine similarly affected visual function in glaucoma, despite differing pressure reductions. Betaxolol marginally outperformed timolol in blue-yellow sensitivity, suggesting pressure reduction doesn't always correlate with visual function preservation.

Broadway D C, Drance S M

This study found focal ischemic glaucoma is linked to vasospasm and cold extremities, while senile sclerotic glaucoma correlates with cardiovascular disease. This suggests specific glaucoma subtypes have distinct systemic risk factors, guiding tailored patient assessment.

Drance S M, Crichton A, Mills R P

Latanoprost increased ocular perfusion pressure more favorably than timolol in normal-tension glaucoma patients, as timolol reduced systemic blood pressure. This suggests latanoprost may be better for ocular blood flow.

Broadway D C, Drance S M, Parfitt C M, Mikelberg F S

SLO distinguished glaucoma disk types, but its ability to detect damage varied significantly among them, highlighting the ongoing importance of expert clinical assessment.

Iester M, Broadway D C, Mikelberg F S, Drance S M

This study compared optic disc parameters, finding ocular hypertensive discs indistinguishable from healthy ones, while glaucomatous discs significantly differed, with disc size having limited impact on differentiation.

Johnson C A, Cioffi G A, Drance S M, Gaasterland D, Mills R P, Ashburn F et al.

This study found Humphrey Field Analyzer I and II provide equivalent visual field results, meaning they can be used interchangeably for patient monitoring and clinical trials.

Zhang L, Drance S M, Douglas G R

Studying glaucoma patients, 10-2 perimetry found that one-third of central 30-2 defects weren't imminent fixation threats. This extra test helps avoid premature, radical treatment changes.

Yamazaki Y, Drance S M

This study found that progressive vision loss in normal-tension glaucoma is linked to worse retrobulbar blood flow, suggesting circulation plays a key role in its progression.

Zhang L, Drance S M, Douglas G R

The Medmont M600 accurately detected paracentral glaucoma defects (78-95% sensitivity, 81-83% specificity) in 36% less time than Humphrey 10-2, offering an efficient clinical alternative.

Nicolela M T, Hnik P, Schulzer M, Drance S M

This study found scanning laser Doppler flowmetry (SLDF) reproducibly measures retinal and lamina cribrosa blood flow, particularly with a 10x10 pixel target, which is clinically relevant for monitoring glaucoma.

Drance S M

Iester M, Mikelberg F S, Courtright P, Drance S M

This study found that Heidelberg Retina Tomograph (HRT) rim area strongly correlates with visual field damage in glaucoma, suggesting it's a key indicator of optic nerve health.

Iester M, Mikelberg F S, Drance S M

This study found the HRT detected glaucoma well, but its diagnostic precision was lower for unusually small optic discs, highlighting a clinical challenge in these cases.

Greve E L, Rulo A H, Drance S M, Crichton A C, Mills R P, Hoyng P F

Latanoprost was studied in normal tension glaucoma. Once-daily 0.005% latanoprost significantly reduced IOP and improved ocular perfusion pressure, suggesting it's a promising, convenient treatment for NTG.

Nicolela M T, Hnik P, Drance S M

This study found POAG patients have reduced blood flow, volume, and velocity in the lamina cribrosa and upper temporal retina, suggesting vascular compromise contributes to glaucoma pathogenesis.

Nicolela M T, Buckley A R, Walman B E, Drance S M

This study found that while timolol and latanoprost both lower IOP, neither significantly altered retrobulbar blood flow in glaucoma/ocular hypertension patients, suggesting minimal vascular impact.

Graham S L, Drance S M, Chauhan B C, Swindale N V, Hnik P, Mikelberg F S et al.

This study compared various tests for early glaucoma, finding pattern ERG and letter acuity tests best for detection, suggesting they can improve early diagnosis, even before visual field defects appear.

Nicolela M T, Walman B E, Buckley A R, Drance S M

This study found that glaucoma patients with senile sclerotic optic discs have significantly worse retrobulbar blood flow, suggesting circulatory abnormalities may contribute to their glaucoma pathogenesis.